De novo transcriptome assembly and gene annotation for the toxic dinoflagellate Dinophysis. [PDF]
Sci Data, 2023 Gaonkar CC, Campbell L.
europepmc +1 more source
GOChase: correcting errors from Gene Ontology-based annotations for gene products [PDF]
, 2004 Yu Rang Park, Chan Hee Park, Ju Han Kim
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Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Annotation of Genes Involved in Glycerolipid Biosynthesis in Chlamydomonas reinhardtii : Discovery of the Betaine Lipid Synthase BTA1 Cr [PDF]
, 2005 Wayne R. Riekhof +2 more
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A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Automatic Prediction and Annotation: There Are Strong Biases for Multigenic Families
Frontiers in Genetics, 2021 Catherine Mathé, Christophe Dunand
doaj +1 more source
Benchmarking cell type annotation methods for 10x Xenium spatial transcriptomics data
BMC BioinformaticsBackground Imaging-based spatial transcriptomics technologies allow us to explore spatial gene expression profiles at the cellular level. Cell type annotation of imaging-based spatial data is challenging due to the small gene panel, but it is a crucial ...
Jinming Cheng +3 more
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Nanopore PCR-cDNA sequencing of the biocontrol isolate Aspergillus flavus AF36 (NRRL 18543) informs gene annotation. [PDF]
Microbiol Resour Announc, 2023 Legan AW +3 more
europepmc +1 more source
Phydbac "Gene Function Predictor" : a gene annotation tool based on genomic context analysis [PDF]
, 2005 François Enault +2 more
openalex +1 more source