Results 181 to 190 of about 7,510,778 (382)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

lncRNA gene annotation v1

, 2018
lncRNA gene annotation pipeline
openaire   +1 more source

Improved white spruce (Picea glauca) genome assemblies and annotation of large gene families of conifer terpenoid and phenolic defense metabolism [PDF]

, 2015
René L. Warren, Christopher I. Keeling, Macaire M. S. Yuen, Anthony Raymond, Greg Taylor, Benjamin P. Vandervalk, Hamid Mohamadi, Daniel Paulino, Readman Chiu, Shaun D. Jackman, Gordon Robertson, Chen Yang, Brian Boyle, Margarete Hoffmann, Detlef Weigel, David R. Nelson, Carol Ritland, Nathalie Isabel, Barry Jaquish, Alvin D. Yanchuk, Jean Bousquet, Steven J.M. Jones, John Mackay, İnanç Birol, Jöerg Bohlmann   +24 more
openalex   +1 more source

Predicting molecular initiating events using chemical target annotations and gene expression [PDF]

, 2022
Joseph L. Bundy, Richard Judson, Antony Williams, Chris Grulke, Imran Shah, Logan J. Everett   +5 more
openalex   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Characteristics and Phylogenetic Considerations of the Newly Sequenced Mitochondrial Genome of Teratoscincus scincus (Gekkota: Sphaerodactylidae)

Biology
Sphaerodactylidae play a crucial role in ecosystems, possessing significant ecological, scientific, and conservation value. They contribute to pest control and the maintenance of ecological balance, and also provide abundant materials for research in ...
Zhiqiang Ge, Zhengyu Zhang, Zelu Mu, Linqiang Zhong   +3 more
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

The Coffee Genome Hub : [W185] [PDF]

, 2014
The whole genome sequence of Coffea canephora, the perennial diploid species known as Robusta, has been recently obtained and portends to be published and released in the coming months.
Bocs, Stéphanie, Cotta, Michelle G., Dereeper, Alexis, Droc, Gaëtan, Guignon, Valentin, Lashermes, Philippe, Ravel, Sébastien, This, Dominique   +7 more
core  

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data [PDF]

, 2015
Beverley B Matthews, Gilberto dos Santos, Madeline A. Crosby, David Emmert, Susan E. St. Pierre, L. Sian Gramates, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, Victor Strelets, Susan Russo, William M Gelbart   +11 more
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source