Results 241 to 250 of about 54,378 (282)

Genome-Wide DNA Methylation Profiling of Triple-Negative Breast Cancer Uncovers Epigenetic Biomarkers of Tumor Identity and the Immune Microenvironment

Sasiain I, Nacer DF, Jönsson M, Vallon-Christersson J, Giorgiadis A, Aine M, Staaf J.   +6 more
europepmc   +1 more source

Diverse aadA gene cassettes on class 1 integrons introduced into soil via spread manure

Research in Microbiology, 2009
Class 1 integrons are assumed to play an important role in dissemination of antibiotic resistance genes. Class 1 integrons from clinical isolates often have 5′- and 3′-conserved segments flanking the variable region where gene cassettes integrate ...
Holger Heuer, Kornélia Smalla
exaly   +2 more sources

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Origins of the mobile gene cassettes found in integrons

Trends in Microbiology, 1997
Many of the acquired antibiotic resistance genes found in enterobacteria and pseudomonads are part of small mobile elements known as gene cassettes, and other genes are also likely to be found in cassettes. The origins of the genes and the recombination sites that make up cassettes are not known, but recent analyses of available data suggest that ...
Gavin D Recchia, Ruth M Hall
exaly   +3 more sources

Mobile Gene Cassettes and Integrons in Evolution

Annals of the New York Academy of Sciences, 1999
ABSTRACT: Integrons and the site‐specific recombination systems encoded by them provide a simple mechanism for the addition of new genes to bacterial chromosomes. Although there is substantial divergence among the four known integron‐encoded integrases, they all recognize the recombination sites, known as 59‐base elements, that are associated with ...
R M, Hall, C M, Collis, M J, Kim, S R, Partridge, G D, Recchia, H W, Stokes   +5 more
openaire   +2 more sources

Cloning cassettes containing the reporter gene xylE

Gene, 1994
Two pUC-derived vectors containing the promoterless xylE gene (encoding catechol 2,3-dioxygenase) of Pseudomonas putida mt-2 were constructed. The t(o) transcriptional terminator of phage lambda was placed downstream from the stop codon of xylE. The new vectors, pXT1 and pXT2, contain xylE and the t(o) terminator within a cloning cassette which can be ...
Clark E., CIRVILLERI, Gabriella
openaire   +3 more sources

Evolution of ATP-binding cassette transporter genes

Current Opinion in Genetics & Development, 1995
The transport of molecules across lipid membranes is an essential function of all living organisms. One of the families of genes that have evolved to carry out this function is that which encodes the ATP-binding cassette proteins. These molecules use active transport to pump specific molecules across membranes, and the genes that encode them are found ...
M, Dean, R, Allikmets
openaire   +2 more sources

Integrons and gene cassettes: hotspots of diversity in bacterial genomes

Annals of the New York Academy of Sciences, 2012
Integrons are genetic units found in many bacterial species that are defined by their ability to capture small mobile elements called gene cassettes. Cassettes usually contain only one gene, potentially any gene, and an attC recombination site, and thousands of cassettes have been sequenced.
Ruth M Hall
exaly   +3 more sources

Mobile Gene Cassettes and Integrons

Molecular Biology, 2002
Integrons are unique natural systems for capturing and spreading the antibiotic resistance genes among Gram-negative bacteria. Gene transfer into small genomes and into plasmids is via site-specific recombination. Integrons act as receptors of antibiotic resistance cassettes.
openaire   +1 more source