Results 11 to 20 of about 519,971 (295)
Gene drive: progress and prospects [PDF]
Proceedings of the Royal Society B: Biological Sciences, 2019 Gene drive is a naturally occurring phenomenon in which selfish genetic elements manipulate gametogenesis and reproduction to increase their own transmission to the next generation. Currently, there is great excitement about the potential of harnessing such systems to control major pest and vector populations.
Wedell, N, Price, T A R, Lindholm, A K
core +8 more sources
Principles for gene drive research [PDF]
Science, 2017 Sponsors and supporters of gene drive research respond to a National Academies ...
Claudia, Emerson +3 more
openaire +3 more sources
Gene Drive: Evolved and Synthetic [PDF]
ACS Chemical Biology, 2018 Drive is a process of accelerated inheritance from one generation to the next that allows some genes to spread rapidly through populations even if they do not contribute to-or indeed even if they detract from-organismal survival and reproduction. Genetic elements that can spread by drive include gametic and zygotic killers, meiotic drivers, homing ...
Burt, Austin, Crisanti, Andrea
openaire +5 more sources
Journal of Responsible Innovation, 2017 When scientists alter the genome of an organism, we typically reduce its ability to reproduce in the wild.
John Min +3 more
openaire +3 more sources
Driving down malaria transmission with engineered gene drives
Frontiers in Genetics, 2022 The last century has witnessed the introduction, establishment and expansion of mosquito-borne diseases into diverse new geographic ranges. Malaria is transmitted by female Anopheles mosquitoes.
William T. Garrood +5 more
doaj +4 more sources
Gene drive communication: exploring experts’ lived experience of metaphor use
New Genetics and Society, 2022 Metaphors have been crucial in making genetics and genomics public, from the code and the book of life to genetic scissors and gene surgery. A new field is emerging called “gene drive” – a range of controversial technologies that can potentially be used ...
Brigitte Nerlich, Aleksandra Stelmach
doaj +3 more sources
Gene Drive: Past, Present and Future Roads to Vertebrate Biocontrol [PDF]
Applied Biosciences, 2023 Scientists have long sought a technology to humanely control populations of damaging invasive pests in a species-specific manner. Gene drive technology could see this become a reality.
Gus R. McFarlane +2 more
doaj +2 more sources
A gene drive is a gene drive: the debate over lumping or splitting definitions. [PDF]
Nat Commun, 2023 We address a controversy over use of the term “gene drive” to include both natural and synthetic genetic elements that promote their own transmission within a population, arguing that this broad definition is both practical and has advantages for risk analysis.
James SL +3 more
europepmc +6 more sources
Gene drives as a response to infection and resistance
Infection and Drug Resistance, 2019 Tuna C Hayirli,1 Peter F Martelli2 1Harvard Medical School, Boston, MA, USA; 2Department of Healthcare Administration, Sawyer Business School, Suffolk University, Boston, MA, USA Abstract: Vector-borne infectious diseases continue to be a major threat to
Hayirli TC, Martelli PF
doaj +5 more sources
Journal of Pure and Applied MicrobiologyMosquito-borne diseases such as malaria, dengue, Zika, chikungunya, and lymphatic filariasis continue to impose enormous health and economic burdens worldwide.
Rajendran Yamini +6 more
doaj +2 more sources