Results 41 to 50 of about 3,726,105 (294)

Gene Drives on the Horizon [PDF]

Applied Biosafety, 2016
In June 2016, the National Academies of Sciences, Engineering, and Medicine published a 220-page report from its multidisciplinary Committee on Gene Drive Research in Non-Human Organisms, which add...
Elizabeth Heitman, Keegan Sawyer, James P. Collins   +2 more
openaire   +2 more sources

Gene Drive Parameters.

, 2021
Gene Drive Parameters.
Samuel E. Champer (8567463), Pablo García-Díaz (3247677), Nathan Oakes (11886455), Philipp W. Messer (8567466), Ronin Sharma (11886458), Jackson Champer (4261381)   +5 more
core   +1 more source

Author Correction: Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding

Nature Communications, 2018
The original version of this Article contained an error in the spelling of the author Jonah B Sacha, which was incorrectly given as Jonah Sacha. These errors have now been corrected in both the PDF and HTML versions of the Article.
Lucy C. Walters, Karl Harlos, Simon Brackenridge, Daniel Rozbesky, Jordan R. Barrett, Vitul Jain, Thomas S. Walter, Chris A. O’Callaghan, Persephone Borrow, Mireille Toebes, Scott G. Hansen, Jonah B. Sacha, Shaheed Abdulhaqq, Justin M. Greene, Klaus Früh, Emily Marshall, Louis J. Picker, E. Yvonne Jones, Andrew J. McMichael, Geraldine M. Gillespie   +19 more
doaj   +1 more source

Evaluation of Hydrogen Peroxide Fumigation and Heat Treatment for Standard Emergency Arthropod Inactivation in BSL-3 Insectaries

Frontiers in Bioengineering and Biotechnology, 2020
Climate change and global movements of people and goods have accelerated the spread of invasive species, including insects that vector infectious diseases, which threaten the health of more than half of the world’s population. Increasing research efforts
Irina Häcker, Irina Häcker, Roland Koller, Gerrit Eichner, Jakob Martin, Eleni Liapi, Johanna Rühl, Tanja Rehling, Marc F. Schetelig, Marc F. Schetelig   +9 more
doaj   +1 more source

Genomically informed gene drive modelling

, 2022
© 2022 Benjamin James CammCRISPR/Cas gene drives are a focus of genetic biocontrol for pest species. They have the potential to radically affect pest species, by making them more manageable or by eradicating them.
Camm, Benjamin James
core   +1 more source

Gene drive systems: do they have a place in agricultural weed management? [PDF]

, 2018
There is a pressing need for novel control techniques in agricultural weed management. Direct genetic control of agricultural pests encompasses a range of techniques to introduce and spread novel, fitness-reducing genetic modifications through pest ...
Neve, P., Paul Neve
core   +1 more source

Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding

Nature Communications, 2018
Human leucocyte antigen E (HLA-E) directly engages NK cells but also presents antigen to CD8+ T cells. Here the authors show crystal structures of HLA-E in complex with peptides derived from HIV and Mycobacterium tuberculosis, and describe binding ...
Lucy C. Walters, Karl Harlos, Simon Brackenridge, Daniel Rozbesky, Jordan R. Barrett, Vitul Jain, Thomas S. Walter, Chris A. O’Callaghan, Persephone Borrow, Mireille Toebes, Scott G. Hansen, Jonah B Sacha, Shaheed Abdulhaqq, Justin M. Greene, Klaus Früh, Emily Marshall, Louis J. Picker, E. Yvonne Jones, Andrew J. McMichael, Geraldine M. Gillespie   +19 more
doaj   +1 more source

Molecular safeguarding of CRISPR gene drive experiments

eLife, 2019
CRISPR-based homing gene drives have sparked both enthusiasm and deep concerns due to their potential for genetically altering entire species. This raises the question about our ability to prevent the unintended spread of such drives from the laboratory ...
Jackson Champer, Joan Chung, Yoo Lim Lee, Chen Liu, Emily Yang, Zhaoxin Wen, Andrew G Clark, Philipp W Messer   +7 more
doaj   +1 more source

Gene drive strategies of pest control in agricultural systems: Challenges and opportunities

Evolutionary Applications, 2021
Recent advances in gene‐editing technologies have opened new avenues for genetic pest control strategies, in particular around the use of gene drives to suppress or modify pest populations. Significant uncertainty, however, surrounds the applicability of
Mathieu Legros, John M. Marshall, Sarina Macfadyen, Keith R. Hayes, Andy Sheppard, Luke G. Barrett   +5 more
doaj   +1 more source

Regulating gene drives [PDF]

Science, 2014
Regulatory gaps must be filled before gene drives could be used in the ...
Oye, Kenneth A., Esvelt, Kevin, Appleton, Evan, Catteruccia, Flaminia, Church, George, Kuiken, Todd, Lightfoot, Shlomiya Bar-Yam, McNamara, Julie, Smidler, Andrea, Collins, James P.   +9 more
openaire   +1 more source