Results 231 to 240 of about 1,025,168 (353)

A predatory gene drive for targeted control of self-transmissible plasmids. [PDF]

Sci Adv
Tsoi R, Son HI, Hamrick GS, Tang K, Bethke JH, Lu J, Maddamsetti R, You L.   +7 more
europepmc   +1 more source

Expansions to the MGDrivE suite for simulating the efficacy of novel gene-drive constructs in the control of mosquito-borne diseases. [PDF]

BMC Res Notes, 2023
Bennett JB, Wu SL, Chennuri PR, Myles KM, Ndeffo-Mbah ML.   +4 more
europepmc   +1 more source

Lethal gene drive selects inbreeding [PDF]

, 2017

openalex   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Mutant allele formation and inheritance during Cas9/guide RNA-mediated gene drive in a population modification mosquito strain for human malaria control. [PDF]

Genetics
Carballar-Lejarazú R, Pham TB, Tushar T, James AA.   +3 more
europepmc   +1 more source

A Synergistic Transcriptional Regulation of Olfactory Genes Drives Blood-Feeding Associated Complex Behavioral Responses in the Mosquito Anopheles culicifacies

, 2018
Tanwee Das De, Tina Thomas, Sonia Verma, Deepak Singla, Charu Chauhan, Vartika Srivastava, Punita Sharma, Seena Kumari, Sanjay Tevatiya, Jyoti Rani, Yasha Hasija, Kailash C. Pandey, Rajnikant Dixit   +12 more
openalex   +1 more source

Myc cooperates with beta-catenin to drive gene expression in the nephron progenitor cells [PDF]

, 2017
Xinchao Pan, Courtney M. Karner, Thomas J. Carroll   +2 more
openalex   +1 more source

Gene drive-mediated population elimination for biodiversity conservation. When you come to a fork in the road, take it

, 2022
Bruce A. Hay, Ming Guo
openalex   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Gene drive-based population suppression in the malaria vector Anopheles stephensi. [PDF]

Nat Commun
Xu X, Chen J, Wang Y, Liu Y, Zhang Y, Yang J, Yang X, Chen B, He Z, Champer J.   +9 more
europepmc   +1 more source