Results 41 to 50 of about 189,147 (282)
PLoS Computational Biology, 2021 Interest in gene drive technology has continued to grow as promising new drive systems have been developed in the lab and discussions are moving towards implementing field trials.
Sean L Wu +5 more
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Benefits and risks of gene drives for invasive plant management - the case for common tansy
Frontiers in Agronomy, 2023 Invasive plants cause significant environmental and economic damage, but land managers have few control options. Common tansy (Tanacetum vulgare) is prevalent in many US states and is one of the most reported invasive plants in Minnesota.
Lori Croghan +4 more
doaj +1 more source
BioTechniques, 2020 CRISPR/Cas9 technology is a powerful tool for the design of gene-drive systems to control and/or modify mosquito vector populations; however, CRISPR/Cas9-mediated nonhomologous end joining mutations can have an important impact on generating alleles ...
Rebeca Carballar-Lejarazú +4 more
doaj +1 more source
Gates Open ResearchGene drive technology has been recognized for its potential to provide durable and cost-effective solutions for previously intractable problems in public health, conservation, and agriculture.
Kristy Hackett +6 more
doaj +1 more source
Gene drives for schistosomiasis transmission control.
PLoS Neglected Tropical Diseases, 2019 Schistosomiasis is one of the most important and widespread neglected tropical diseases (NTD), with over 200 million people infected in more than 70 countries; the disease has nearly 800 million people at risk in endemic areas.
Theresa Maier +12 more
doaj +1 more source
Modeling the efficacy of CRISPR gene drive for snail immunity on schistosomiasis control.
PLoS Neglected Tropical Diseases, 2022 CRISPR gene drives could revolutionize the control of infectious diseases by accelerating the spread of engineered traits that limit parasite transmission in wild populations.
Richard E Grewelle +5 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Scientific Reports, 2023 Social insects are very successful invasive species, and the continued increase of global trade and transportation has exacerbated this problem. The yellow-legged hornet, Vespa velutina nigrithorax (henceforth Asian hornet), is drastically expanding its ...
Adriaan B. Meiborg +4 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source