Results 141 to 150 of about 6,867,088 (372)
100 million years of multigene family evolution: origin and evolution of the avian MHC class IIB
BMC Genomics, 2017 Background Gene duplication has led to a most remarkable adaptation involved in vertebrates’ host-pathogen arms-race, the major histocompatibility complex (MHC).
Julien Goebel +8 more
doaj +1 more source
Gene duplication as a mechanism of genomic adaptation to a changing environment
Proceedings of the Royal Society B: Biological Sciences, 2012 A subject of extensive study in evolutionary theory has been the issue of how neutral, redundant copies can be maintained in the genome for long periods of time.
F. Kondrashov
semanticscholar +1 more source
Correlation Between Irisin and Cognitive Functions in Alzheimer Dementia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The myokine irisin, a recent positive mediator of exercise in the brain, shows neuroprotective functions against Alzheimer's disease (AD). The association between irisin and cognition has never been explored in a biologically defined cohort of patients.
Patrizia Pignataro +12 more
wiley +1 more source
Organisation, sequence diversity and evolution of a disease-resistance gene cluster in coffee tree (Coffea l.) [PDF]
, 2008 Pathogen resistance (R) genes of the NBS-LRR class (for nucleotide binding site and leucine-rich repeat) are found in all plant species and confer resistance to a diverse spectrum of pathogens.
Combes, Marie-Christine +4 more
core
Bioinform., 2012 Motivation: Gene family evolution is driven by evolutionary events such as speciation, gene duplication, horizontal gene transfer and gene loss, and inferring these events in the evolutionary history of a given gene family is a fundamental problem in ...
M. Bansal, E. Alm, Manolis Kellis
semanticscholar +1 more source
GENE ACTION AND POSITION EFFECT IN DUPLICATIONS IN DROSOPHILA MELANOGASTER [PDF]
, 1954 F.J. Ratty
openalex +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The Apolipoprotein (APOE) ε4 allele is the strongest genetic risk factor for late‐onset Alzheimer's disease (AD); however, many ε4 carriers remain cognitively intact into old age. Leveraging plasma neuron‐derived extracellular vesicles (NDEVs), we sought to identify biomarkers of cognitive resilience and their interplay with APOE ...
Apostolos Manolopoulos +17 more
wiley +1 more source
Gone with the Species: From Gene Loss to Gene Extinction
Frontiers in Bioscience-ScholarBackground: Vertebrae protein-coding genes exhibit remarkable diversity and are organized into many gene families. These gene families have emerged through various gene duplication events, the most prominent being the two rounds of ...
Ammad Aslam Khan, Anees Fatima
doaj +1 more source
Unified modeling of gene duplication, loss, and coalescence using a locus tree.
Genome Research, 2012 Gene phylogenies provide a rich source of information about the way evolution shapes genomes, populations, and phenotypes. In addition to substitutions, evolutionary events such as gene duplication and loss (as well as horizontal transfer) play a major ...
Matthew D. Rasmussen, Manolis Kellis
semanticscholar +1 more source
DEFICIENCY AND DUPLICATIONS FOR THE GENE BOBBED IN DROSOPHILA MELANOGASTER [PDF]
, 1933 N P Sivertzev-Dobzhansky, Th. Dobzhansky
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