Results 171 to 180 of about 172,476 (315)

Endometrial Assembloid Model Reveals Endometrial Gland Development Regulation by Estradiol‐Driven WNT7B Suppression

Advanced Science, EarlyView.
This study developed a 3D endometrial assembloid model to study how uterine glands form and develop. They discovered key interactions between different cell types and identified WNT7B as a regulator controlled by estradiol‐mediated TGFβ1‐VDR interaction.
Xintong Li, Yanjie Guo, Jianlin Li, Yimeng Li, Leqian Lin, Hoi Kit Matthew Leung, Qingqing Zhang, Kai‐Fai Lee, Ka‐Wang Cheung, Ernest H. Y. Ng, William S. B. Yeung, Philip C. N. Chiu, Cheuk‐Lun Lee   +12 more
wiley   +1 more source

Prevalence of Plasmodium falciparum plasmepsin2/3 gene duplication in Africa and Asia: a systematic review and meta-analysis. [PDF]

Malar J
Marwa KJ, Kilonzi M, Mnkugwe RH, Baraka V, Kapesa A, Mwaiswelo R, Zinga M, Mmbando BP, Lusingu JPA, Kamugisha E.   +9 more
europepmc   +1 more source

Colour polymorphism associated with a gene duplication in male wood tiger moths. [PDF]

Elife, 2023
Brien MN, Orteu A, Yen EC, Galarza JA, Kirvesoja J, Pakkanen H, Wakamatsu K, Jiggins CD, Mappes J.   +8 more
europepmc   +1 more source

Genome evolution: Gene duplication and the resolution of adaptive conflict [PDF]

, 2008
Jay F. Storz
openalex   +1 more source

Wedelolactone, a Novel TLR2 Agonist, Promotes Neutrophil Differentiation and Ameliorates Neutropenia: A Multi‐Omics Approach to Unravel the Mechanism

Advanced Science, EarlyView.
Wedelolactone (WED), a natural TLR2 agonist, promotes neutrophil differentiation and enhances bactericidal function, offering a potential therapeutic strategy for neutropenia. Using a multi‐omics approach, this study reveals that WED activates the TLR2/MEK/ERK pathway, upregulating key transcription factors (PU.1, CEBPβ) to drive neutrophil development.
Long Wang, Zhichao Li, Tianci Hu, Qinyao Li, Linwei Zhang, Xinyue Mei, Xiao Qi, Sheng Liu, Weijie Kong, Jiesi Luo, Anguo Wu, Feihong Huang, Sirui Li, Shuang Dai, Chunxiang Zhang, Rong Li, Jianming Wu   +16 more
wiley   +1 more source

ERCnet: Phylogenomic Prediction of Interaction Networks in the Presence of Gene Duplication. [PDF]

Mol Biol Evol
Forsythe ES, Gatts TC, Lane LE, deRoux C, Berggren MJ, Rehmann EA, Zak EN, Bartel T, L'Argent LA, Sloan DB.   +9 more
europepmc   +1 more source

Gene duplication as a major force driving the genome expansion in some giant viruses. [PDF]

J Virol, 2023
Machado TB, Picorelli ACR, de Azevedo BL, de Aquino ILM, Queiroz VF, Rodrigues RAL, Araújo JP, Ullmann LS, Dos Santos TM, Marques RE, Guimarães SL, Andrade ACSP, Gularte JS, Demoliner M, Filippi M, Pereira VMAG, Spilki FR, Krupovic M, Aylward FO, Del-Bem L-E, Abrahão JS.   +20 more
europepmc   +1 more source

Metallothionein Gene Duplications and Metal Tolerance in Natural Populations of Drosophila melanogaster

, 2020
G. Maroni
openalex   +1 more source

A Cold Stress‐Activated Endocrine Sentinel Chemical Hormone Promotes Insect Survival via Mitochondrial Adaptations Through the Adipokinetic Hormone Receptor

Advanced Science, EarlyView.
Seasonal cold adaptation is vital for insect survival, yet the molecular mechanisms linking diapause to mitochondrial resilience remain largely unresolved. We identify ascaroside C9 (asc‐C9) as a key endocrine signal that enhances diapause survival during cold stress by activating the AKHR–PGC1α–UCP4 axis, thereby driving cold‐induced lipolysis and ...
Jiao Zhou, Junxian Chen, Hongxia Zhang, Lu Guo, Kevin Mai, Elijah Abraham, Dilip V. Prajapati, Yue Chang, Jing Ning, Xinchen Wang, Defeng Li, Dan‐Dan Zhang, Jianghua Sun, Rebecca A. Butcher, Lilin Zhao   +14 more
wiley   +1 more source

Apparent Nonresponse to PCSK9 Inhibition in a Patient With Heterozygous Familial Hypercholesterolemia Due to PCSK9 Gene Duplication. [PDF]

JACC Case Rep
Pindwarawala M, Bose S, Brunham LR.
europepmc   +1 more source