Results 11 to 20 of about 194,146 (309)
The shape of human gene family phylogenies [PDF]
BMC Evolutionary Biology, 2006 Background The shape of phylogenetic trees has been used to make inferences about the evolutionary process by comparing the shapes of actual phylogenies with those expected under simple models of the speciation process.
Cotton James A, Page Roderic DM
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Inferring duplication episodes from unrooted gene trees [PDF]
BMC Genomics, 2018 Background One of evolutionary molecular biology fundamental issues is to discover genomic duplication events and their correspondence to the species tree.
Jarosław Paszek, Paweł Górecki
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Muller’s ratchet and gene duplication [PDF]
Theoretical Population BiologyCopy number of genes in gene families can be highly variable among individuals and may continue to change across generations. Here, we study a model of duplication-selection interaction, which is related to Haigh’s mutation-selection model of Muller’s ratchet.
Fabian Freund +4 more
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Gene duplication to the Y chromosome in Trinidadian Guppies [PDF]
, 2022 Differences in allele frequencies at autosomal genes between males and females in a population can result from two scenarios. First, unresolved sexual conflict over survival can produce allelic differentiation between the sexes.
Mank, JE +23 more
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Promoter evolution of mammalian gene duplicates
BMC Biology, 2023 Background Gene duplication is thought to be a central process in evolution to gain new functions. The factors that dictate gene retention following duplication as well paralog gene divergence in sequence, expression and function have been extensively ...
Evgeny Fraimovitch, Tzachi Hagai
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Acquisition of new function through gene duplication in the metallocarboxypeptidase family
Scientific Reports, 2023 Gene duplication is a key first step in the process of expanding the functionality of a multigene family. In order to better understand the process of gene duplication and its role in the formation of new enzymes, we investigated recent duplication ...
Daniel Fajardo +2 more
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Mechanisms of gene duplication and translocation and progress towards understanding their relative contributions to animal genome evolution [PDF]
, 2012 Duplication of genetic material is clearly a major route to genetic change, with consequences for both evolution and disease. A variety of forms and mechanisms of duplication are recognised, operating across the scales of a few base pairs upto entire ...
Mendivil Ramos, Olivia +1 more
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BMC Genomics, 2012 Background Gene duplication has had a major impact on genome evolution. Localized (or tandem) duplication resulting from unequal crossing over and whole genome duplication are believed to be the two dominant mechanisms contributing to vertebrate genome ...
Lu Jianguo +4 more
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Horizontal transfer, not duplication, drives the expansion of protein families in prokaryotes. [PDF]
PLoS Genetics, 2011 Gene duplication followed by neo- or sub-functionalization deeply impacts the evolution of protein families and is regarded as the main source of adaptive functional novelty in eukaryotes.
Todd J Treangen, Eduardo P C Rocha
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Towards more biological mutation operators in gene regulation studies [PDF]
, 2003 Genetic regulation is often viewed as a complex system whose properties emerge from the interaction of regulatory genes. One major paradigm for studying the complex dynamics of gene regulation uses directed graphs to explore structure, behaviour and ...
Wiles, J. +11 more
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