Results 11 to 20 of about 3,440,639 (300)
The shape of human gene family phylogenies [PDF]
Background The shape of phylogenetic trees has been used to make inferences about the evolutionary process by comparing the shapes of actual phylogenies with those expected under simple models of the speciation process.
Cotton James A, Page Roderic DM
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Gene duplication and evolution in recurring polyploidization–diploidization cycles in plants
Background The sharp increase of plant genome and transcriptome data provide valuable resources to investigate evolutionary consequences of gene duplication in a range of taxa, and unravel common principles underlying duplicate gene retention. Results We
Xin Qiao +7 more
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Algorithms: simultaneous error-correction and rooting for gene tree reconciliation and the gene duplication problem [PDF]
Background Evolutionary methods are increasingly challenged by the wealth of fast growing resources of genomic sequence information. Evolutionary events, like gene duplication, loss, and deep coalescence, account more then ever for incongruence between ...
Górecki Pawel, Eulenstein Oliver
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On the Multiple Gene Duplication Problem
A fundamental problem in computational biology is the determination of the correct species tree for a set of taxa given a set of (possibly contradictory) gene trees. In recent literature, the DUPLICATION/ LOSS model has received considerable attention. Here one measures the similarity/dissimilarity between a set of gene trees by counting the number of ...
Michael R. Fellows +2 more
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Muller’s ratchet and gene duplication [PDF]
Copy number of genes in gene families can be highly variable among individuals and may continue to change across generations. Here, we study a model of duplication-selection interaction, which is related to Haigh’s mutation-selection model of Muller’s ratchet.
Fabian Freund +4 more
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Expectations of Duplicate Gene Retention Under the Gene Duplicability Hypothesis
Abstract Background Gene duplication is an important process in evolution. What causes some genes to be retained after duplication and others to be lost is a process not well understood. The most prevalent theory is the gene duplicability hypothesis, that something about the function and number of interacting partners (number of subunits of ...
Amanda E. Wilson, David A. Liberles
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Counting Subnetworks Under Gene Duplication in Genetic Regulatory Networks. [PDF]
Gene duplication is a fundamental evolutionary mechanism that contributes to biological complexity and diversity (Fortna et al., 2004). Traditionally, research has focused on the duplication of gene sequences (Zhang, 1914).
Scruse A, Arnold J, Robinson R.
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Gene Complexity and Gene Duplicability [PDF]
Eukaryotic genes are on average more complex than prokaryotic genes in terms of expression regulation, protein length, and protein-domain structure [1-5]. Eukaryotes are also known to have a higher rate of gene duplication than prokaryotes do [6, 7]. Because gene duplication is the primary source of new genes [], the average gene complexity in a genome
He, Xionglei, Zhang, Jianzhi
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Gene Dosage and Gene Duplicability [PDF]
Abstract The evolutionary process leading to the fixation of newly duplicated genes is not well understood. It was recently proposed that the fixation of duplicate genes is frequently driven by positive selection for increased gene dosage (i.e., the gene dosage hypothesis), because haploinsufficient genes were reported to have more ...
Wenfeng, Qian, Jianzhi, Zhang
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Mechanisms of gene duplication and translocation and progress towards understanding their relative contributions to animal genome evolution [PDF]
Duplication of genetic material is clearly a major route to genetic change, with consequences for both evolution and disease. A variety of forms and mechanisms of duplication are recognised, operating across the scales of a few base pairs upto entire ...
Mendivil Ramos, Olivia +2 more
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