Results 31 to 40 of about 194,146 (309)
Revealing mammalian evolutionary relationships by comparative analysis of gene clusters [PDF]
, 2012 Many software tools for comparative analysis of genomic sequence data have been released in recent decades. Despite this, it remains challenging to determine evolutionary relationships in gene clusters due to their complex histories involving ...
Riemer, C. +20 more
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Frontiers in Pediatrics, 2021 Background: Very few reports are available on human XX ovotesticular disorder of sex development involving SOX3 gene duplication. Here we aim to present a rare case of SOX3 gene duplication in a person from the Chinese population who exhibits XX ...
Jianlong Zhuang +9 more
doaj +1 more source
Selection in the evolution of gene duplications [PDF]
Genome Biology, 2002 Gene duplications have a major role in the evolution of new biological functions. Theoretical studies often assume that a duplication per se is selectively neutral and that, following a duplication, one of the gene copies is freed from purifying (stabilizing) selection, which creates the potential for evolution of a new function.In search of systematic
Fyodor A, Kondrashov +3 more
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Altered patterns of gene duplication and differential gene gain and loss in fungal pathogens
BMC Genomics, 2008 Background Duplication, followed by fixation or random loss of novel genes, contributes to genome evolution. Particular outcomes of duplication events are possibly associated with pathogenic life histories in fungi.
Carbone Ignazio +4 more
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Counting Subnetworks Under Gene Duplication in Genetic Regulatory Networks. [PDF]
Bull Math BiolGene duplication is a fundamental evolutionary mechanism that contributes to biological complexity and diversity (Fortna et al., 2004). Traditionally, research has focused on the duplication of gene sequences (Zhang, 1914).
Scruse A, Arnold J, Robinson R.
europepmc +3 more sources
Evolution of substrate specificity in a recipient's enzyme following horizontal gene transfer [PDF]
, 2013 Despite the prominent role of horizontal gene transfer (HGT) in shaping bacterial metabolism, little is known about the impact of HGT on the evolution of enzyme function.
Noda-Garcia, Lianet +6 more
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Evolution of Gene Duplication in Plants [PDF]
Plant Physiology, 2016 Ancient duplication events and a high rate of retention of extant pairs of duplicate genes have contributed to an abundance of duplicate genes in plant genomes. These duplicates have contributed to the evolution of novel functions, such as the production of floral structures, induction of disease resistance, and adaptation to stress.
Nicholas Panchy +2 more
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Investigation of human centrosomes - with a special focus on the function of Cep152 and Cep192 in centriole duplication [PDF]
, 2012 Centrioles are symmetrical, barrel-shaped, microtubule-based structures, that serve as building platforms for the formation of centrosomes and cilia. In dividing cells, they recruit a matrix of proteins called pericentriolar material (PCM) to form the ...
Sonnen, Katharina Friederike
core +1 more source
Comparative Genomics Reveals Gene Duplication and Evolution in 26 Aurantioideae Species
HorticulturaeGene duplication, as a prevalent phenomenon in the tree of life, provides a potential substrate for evolution. However, its role in the Aurantioideae remains unclear.
Jiaxuan Liu +5 more
doaj +1 more source
Mechanisms of Gene Duplication and Amplification [PDF]
Cold Spring Harbor Perspectives in Biology, 2015 Changes in gene copy number are among the most frequent mutational events in all genomes and were among the mutations for which a physical basis was first known. Yet mechanisms of gene duplication remain uncertain because formation rates are difficult to measure and mechanisms may vary with position in a genome.
Reams, Andrew B, Roth, John R
openaire +4 more sources