Results 21 to 30 of about 194,146 (309)

The roles of segmental and tandem gene duplication in the evolution of large gene families in Arabidopsis thaliana

BMC Plant Biology, 2004
Background Most genes in Arabidopsis thaliana are members of gene families. How do the members of gene families arise, and how are gene family copy numbers maintained?
Baumgarten Andrew, Mitra Arvind, Cannon Steven B, Young Nevin D, May Georgiana   +4 more
doaj   +1 more source

Evolution of a complex locus : exon gain, loss and divergence at the Gr39a locus in Drosophila [PDF]

, 2008
Background. Gene families typically evolve by gene duplication followed by the adoption of new or altered gene functions. A different way to evolve new but related functions is alternative splicing of existing exons of a complex gene.
Butlin, Roger K., Gardiner, Anastasia, Gardiner, A., Jordan, W.C., Ritchie Michael G., Ritchie, M.G., Jordan, William C., Michael G Ritchie, Barker, Daniel, William C Jordan, Barker, D., Ritchie, Michael G., Gardiner Anastasia, Daniel Barker, Anastasia Gardiner, Barker Daniel, Roger K Butlin, Jordan William C., Butlin, R.K., Butlin Roger K.   +19 more
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Gene duplication and evolution in recurring polyploidization–diploidization cycles in plants

Genome Biology, 2019
Background The sharp increase of plant genome and transcriptome data provide valuable resources to investigate evolutionary consequences of gene duplication in a range of taxa, and unravel common principles underlying duplicate gene retention. Results We
Xin Qiao, Qionghou Li, Hao Yin, Kaijie Qi, Leiting Li, Runze Wang, Shaoling Zhang, Andrew H. Paterson   +7 more
doaj   +1 more source

Models for the retention of duplicate genes and their biological underpinnings [version 1; peer review: 2 approved]

F1000Research, 2023
Gene content in genomes changes through several different processes, with gene duplication being an important contributor to such changes. Gene duplication occurs over a range of scales from individual genes to whole genomes, and the dynamics of this ...
Amanda E. Wilson, David A. Liberles, Malgorzata M. O'Reilly, Gavin Conant, Barbara Holland, Raquel Assis   +5 more
doaj   +1 more source

Independent large scale duplications in multiple M. tuberculosis lineages overlapping the same genomic region [PDF]

, 2012
Mycobacterium tuberculosis, the causative agent of most human tuberculosis, infects one third of the world's population and kills an estimated 1.7 million people a year. With the world-wide emergence of drug resistance, and the finding of more functional
Gagneux, Sebastian, Michael Koehrsen (185361), Bonnie B Plikaytis, van Helden, Paul D., Sisk, P., Stolte, Christian, Hung, D., Jared White, Paul D. van Helden (33594), Gey van Pittius, Nicolass C., Brian Weiner, Gagneux, Sebastien, Gomez James, Bruce Birren, Sisk, Peter, Hung, Deborah, Sloutsky Alexander, White, Jared, Robert M. Warren (185350), Nicolass C. Gey van Pittius (185359), Deborah Hung (185364), Birren, Bruce, Warren, Robert M., Peter Sisk (185362), Galagan, J., van Helden, P. D., Robert M Warren, Nicolass C Gey van Pittius, Bonnie B. Plikaytis (185356), Paul D van Helden, Megan Murray (63415), Birren Bruce, Plikaytis, Bonnie B., Weiner, Brian, Koehrsen Michael, Galagan, James E., Victor Thomas C., Warren, R. M., Sloutsky, A., Bruce Birren (18146), Weiner Brian, Birren, B., Van Pittius, Nicolaas C. Gey, Christian Stolte, Stolte Christian, Gomez, J., Posey James E., Plikaytis Bonnie B., Gagneux, S., Peter Sisk, Brian Weiner (164963), James Gomez (185343), Posey, J. E., Thomas C Victor, Michael Koehrsen, Jared White (185363), Galagan James, Weiner, B., James Gomez, Warren Robert M., Gagneux Sebastien, James Galagan (185365), Murray, M., White Jared, Gey van Pittius, N. C., Galagan, James, James E Posey, White, J., Sloutsky, Alexander, Hung Deborah, Alexander Sloutsky, Stolte, C., James Galagan, Gomez, James, Deborah Hung, Sebastien Gagneux (149824), Plikaytis, B. B., Posey, James E., Koehrsen, M., Warren, Rob, van Helden Paul D., Alexander Sloutsky (185354), Sisk Peter, Sebastien Gagneux, Murray Megan, James E. Posey (155073), Murray, Megan, Megan Murray, Koehrsen, Michael, Victor, Thomas C., Victor, T. C., Christian Stolte (2869), Gey van Pittius Nicolass C., Thomas C. Victor (185348)   +93 more
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Gene duplication and fragmentation in the zebra finch major histocompatibility complex [PDF]

, 2010
BACKGROUND: Due to its high polymorphism and importance for disease resistance, the major histocompatibility complex (MHC) has been an important focus of many vertebrate genome projects.
Tina Graves, Griffin, D.K., Wesley C Warren, Edwards, Scott, Völker, Martin, Völker Martin, Westerdahl Helena, Burt, D.W., Graves, Tina, Griffin Darren K, Martin Völker, Burt, David W, Darren K Griffin, Helena Westerdahl, Godinez Ricardo, Edwards, S.V., Edwards, Scott V, Kotkiewicz, H., Ekblom, Robert,, Ekblom Robert, Warren, Wesley C, Warren, W.C., Ekblom, Robert, Robert Ekblom, David W Burt, Ricardo Godinez, Warren, Wesley C., Scott V Edwards, Lund University., Griffin, Darren K., Godinez, Ricardo, Westerdahl, Helena, Ekblom, R., Westerdahl, Helena,, Edwards, Scott V., Kotkiewicz, Holly, Voelker, Martin, Graves Tina, Christopher N Balakrishnan, Balakrishnan, Christopher N, Godinez, R., Warren Wesley C, Burt David W, Balakrishnan, Christopher N., Kotkiewicz Holly, Griffin, Darren K, Westerdahl, H., Balakrishnan Christopher N, Balakrishnan, C.N., Graves, T., Graves, Tina A., Burt, David W., Holly Kotkiewicz, Volker, M., Edwards Scott V   +54 more
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Copy-number changes in evolution: rates, fitness effects and adaptive significance

Frontiers in Genetics, 2013
Gene copy-number differences due to gene duplications and deletions are rampant in natural populations and play a crucial role in the evolution of genome complexity.
Vaishali eKatju, Ulfar eBergthorsson
doaj   +1 more source

Parallel reorganization of protein function in the spindle checkpoint pathway through evolutionary paths in the fitness landscape that appear neutral in laboratory experiments. [PDF]

PLoS Genetics, 2017
Regulatory networks often increase in complexity during evolution through gene duplication and divergence of component proteins. Two models that explain this increase in complexity are: 1) adaptive changes after gene duplication, such as resolution of ...
Alex N Nguyen Ba, Bob Strome, Selma Osman, Elizabeth-Ann Legere, Taraneh Zarin, Alan M Moses   +5 more
doaj   +1 more source

Glyphosate resistance and EPSPS gene duplication: convergent evolution in multiple plant species [PDF]

, 2018
One of the increasingly widespread mechanisms of resistance to the herbicide glyphosate is copy number variation (CNV) of the 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) gene.
Ravet, K., Pettinga, D.J., Neve, P., Patterson, E.L., Gaines, T.A.   +4 more
core   +1 more source

8p23.1 duplication syndrome differentiated from copy number variation of the defensin cluster at prenatal diagnosis in four new families [PDF]

, 2010
Background: the 8p23.1 duplication syndrome and copy number variation of the 8p23.1 defensin gene cluster are cytogenetically indistinguishable but distinct at the molecular level.
Emma-Jane Taylor, Liehr, Thomas, Susanne Morlot, Joana Trindade, Ocraft, Kevin, Ana I Paramos, Viv K Maloney, Paramos Ana I, Bunyan Dave, Curtis, Merryl, Claudia Alves, Merryl Curtis, Maloney, Viv K., Dermitzel Anette, Bunyan, Dave, Denise Robinson, Dermitzel, Anette, Thomas Liehr, Alves Claudia, John CK Barber, Kevin Ocraft, Taylor, Emma-Jane, Clare Cooper, Alves, Claudia, Taylor Emma-Jane, Anette Dermitzel, Curtis Merryl, Ocraft Kevin, Barber John CK, Cooper Clare, Paramos, Ana I., Cooper, Clare, Liehr Thomas, Barber, John C.K., Robinson, Denise, Trindade Joana, Morlot, Susanne, Morlot Susanne, Robinson Denise, Maloney Viv K, Dave Bunyan, Trindade, Joana   +41 more
core   +1 more source