Results 201 to 210 of about 7,473,287 (361)

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

FEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji, Hae Sung Lee, Haesung Lee, Jong‐Hee Kim   +3 more
wiley   +1 more source

Innovations in Cattle Breeding Technology: Prospects in the Era of Gene Editing. [PDF]

Animals (Basel)
Wang Y, Cui X, Chen Z.
europepmc   +1 more source

Genome editing of BmFib-H gene provides an empty Bombyx mori silk gland for a highly efficient bioreactor [PDF]

, 2014
Sanyuan Ma, Run Shi, Xiaogang Wang, Yuanyuan Liu, Jiasong Chang, Jie Gao, Wei Lü, Jianduo Zhang, Ping Zhao, Qingyou Xia   +9 more
openalex   +1 more source

The CRISPR-Cas toolbox and gene editing technologies.

Molecules and Cells, 2021
Guanwen Liu, Qiupeng Lin, Shuai Jin, Caixia Gao   +3 more
semanticscholar   +1 more source

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source

CRISPR/Cas9 Delivery Systems to Enhance Gene Editing Efficiency. [PDF]

Int J Mol Sci
Seijas A, Cora D, Novo M, Al-Soufi W, Sánchez L, Arana ÁJ.   +5 more
europepmc   +1 more source

Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss

FEBS Open Bio, EarlyView.
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki, Chika Tomisawa, Soichiro Hoshino, Hidehiko Shimizu, Masashi Abe, Sho Arai, Kanako Kuwasako, Naoki Asakawa, Yusuke Inoue, Takuro Horii, Izuho Hatada, Masakatsu Watanabe   +11 more
wiley   +1 more source

Advances in CRISPR/Cas9-Based Gene Editing in Filamentous Fungi. [PDF]

J Fungi (Basel)
Ma B, Li Y, Wang T, Li D, Jia S.
europepmc   +1 more source

Gene editing: how to stay on-target with CRISPR [PDF]

, 2014
Vivien Marx
openalex   +1 more source

GDP‐fucose transporter SLC35C1: a potential regulatory role in cytosolic GDP‐fucose and fucosylated glycan synthesis

FEBS Open Bio, EarlyView.
The inactivation of SLC35C1 (GDP‐fucose transporter) and enzymes involved in GDP‐fucose biosynthesis was studied. Fucose supplementation increases the level of GDP‐fucose to abnormal, millimolar values in the absence of the TSTA3 protein and SLC35C1 in contrast to the GMDS/SLC35C1 double mutant.
Edyta Skurska, Mariusz Olczak
wiley   +1 more source