Results 281 to 290 of about 8,339,405 (403)

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

A simple protocol for transformation and gene editing in woody mangrove plant. [PDF]

Plant Physiol
Weng Y, Hai E, Li QQ.
europepmc   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Harnessing the potential of gene editing technology for CAR-T cell therapy of solid tumors. [PDF]

Inflamm Regen
Khodabandehloo E, Rayati M, Ahmadi E, Naghdibadi M, Moradi V, Ahmadbeigi N.   +5 more
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Nanoparticle-enhanced CRISPR delivery: paving the path for <i>in vivo</i> tumor gene editing. [PDF]

Ann Med Surg (Lond)
Khizar M, Aminpoor H, Zaib M, Ali Q, Karimi H.   +4 more
europepmc   +1 more source

Engraftment of gene-edited hematopoietic stem cells after antibody-drug conjugate conditioning in nonhuman primates [PDF]

Jason Murray, Teresa Einhaus, Stefan Radtke, Katharine J. Bar, Christopher W. Peterson, Hans‐Peter Kiem   +5 more
openalex   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Modification of starch synthesis in food crops using CRISPR/Cas9 gene editing technology for changing climate. [PDF]

Stress Biol
Niu L, Liu H, Wang N, Wu X, Tai F, Hu X, Wang W.   +6 more
europepmc   +1 more source

Health research in the era of artificial intelligence: Advances in gene-editing study

Mengyao Dai, Xiangyang Li, Qí Zhāng, Tingbo Liang, Xingxu Huang, Qihan Fu   +5 more
openalex   +1 more source