Results 31 to 40 of about 13,983,545 (429)
Scientific Reports, 2021 A promising therapy for patients with B-cell lymphoma is based on vaccination with idiotype monoclonal antibodies (mAbs). Since idiotypes are different in each tumor, a personalized vaccine has to be produced for each patient.
Erkuden Casales +11 more
doaj +1 more source
Gene profiling for determining pluripotent genes in a time course microarray experiment [PDF]
Biostatistics, Volume 10, Number 1, 2009, pages 80-93, 2008 In microarray experiments, it is often of interest to identify genes which have a pre-specified gene expression profile with respect to time. Methods available in the literature are, however, typically not stringent enough in identifying such genes, particularly when the profile requires equivalence of gene expression levels at certain time points.
arxiv +1 more source
Wellcome Open Research, 2018 Background: Viral oncogenes and mutated proto-oncogenes are potent drivers of cancer malignancy. Downstream of the oncogenic trigger are alterations in protein properties that give rise to cellular transformation and the acquisition of malignant cellular
Tony Ly +6 more
doaj +1 more source
IMA Fungus, 2011 This contribution is based on the four presentations made at the Special Interest Group (SIG) meeting titled Gene Expression in Fungi held during IMC9 in Edinburgh. This overview is independent from other articles published or that will be published by each speaker.
KALKANCI, AYŞE +3 more
openaire +5 more sources
Establishment of human iPSC-based models for the study and targeting of glioma initiating cells
Nature Communications, 2016 Glioma can originate from the transformation of neural progenitor cells into glioma initiating cells. Here, the authors demonstrate the use of induced pluripotent stem cells as a suitable model for generating neural progenitor cells, which can be ...
Ignacio Sancho-Martinez +22 more
doaj +1 more source
Temporal inhibition of chromatin looping and enhancer accessibility during neuronal remodeling
Nature Communications, 2021 Long-range looping of an enhancer to a promoter (E-P looping) is a key feature of gene activation; thus, regulation of E-P looping could serve as an effective strategy to precisely control gene expression.
Dahong Chen +4 more
doaj +1 more source
Gene Expression Omnibus: NCBI gene expression and hybridization array data repository
Nucleic Acids Res., 2002 The Gene Expression Omnibus (GEO) project was initiated in response to the growing demand for a public repository for high-throughput gene expression data.
Ron Edgar, M. Domrachev, A. Lash
semanticscholar +1 more source
Lentiviral vectors with amplified beta cell-specific gene expression. [PDF]
, 2009 An important goal of gene therapy is to be able to deliver genes, so that they express in a pattern that recapitulates the expression of an endogenous cellular gene.
Crooks, GM +7 more
core +2 more sources
Proceedings of the National Academy of Sciences of the United States of America, 2001 The purpose of this study was to classify breast carcinomas based on variations in gene expression patterns derived from cDNA microarrays and to correlate tumor characteristics to clinical outcome.
T. Sørlie +16 more
semanticscholar +1 more source
Sequencing refractory regions in bird genomes are hotspots for accelerated protein evolution
BMC Ecology and Evolution, 2021 Background Approximately 1000 protein encoding genes common for vertebrates are still unannotated in avian genomes. Are these genes evolutionary lost or are they not yet found for technical reasons?
R. Huttener +11 more
doaj +1 more source