Results 71 to 80 of about 15,770,266 (354)

Novel biosensor for high-throughput detection of progesterone receptor-interacting endocrine disruptors

Scientific Reports
Progesterone receptor (PR)-interacting compounds in the environment are associated with serious health hazards. However, methods for their detection in environmental samples are cumbersome.
Diana A. Stavreva, Lyuba Varticovski, Razi Raziuddin, Gianluca Pegoraro, R. Louis Schiltz, Gordon L. Hager   +5 more
doaj   +1 more source

NetworkAnalyst 3.0: a visual analytics platform for comprehensive gene expression profiling and meta-analysis

Nucleic Acids Res., 2019
The growing application of gene expression profiling demands powerful yet user-friendly bioinformatics tools to support systems-level data understanding.
Guangyan Zhou, O. Soufan, J. Ewald, R. Hancock, N. Basu, J. Xia   +5 more
semanticscholar   +1 more source

Transcriptome-scale spatial gene expression in the human dorsolateral prefrontal cortex

Nature Neuroscience, 2020
We used the 10x Genomics Visium platform to define the spatial topography of gene expression in the six-layered human dorsolateral prefrontal cortex.
K. E. Maynard, L. Collado-Torres, L. Weber, C. Uytingco, B. Barry, S. Williams, J. L. Catallini, M. N. Tran, Z. Besich, M. Tippani, J. Chew, Y. Yin, J. Kleinman, T. Hyde, N. Rao, S. Hicks, Keri Martinowich, A. Jaffe   +17 more
semanticscholar   +1 more source

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider, Amelie Alfert, Marc Hotfilder, Birgit Burkardt, Marcel te Vrugt   +4 more
wiley   +1 more source

Structural basis underlying viral hijacking of a histone chaperone complex

Nature Communications, 2016
The Epstein-Barr virus tegument protein BNRF1 is required for the establishment of selective viral gene expression during latency and interacts with the histone chaperone DAXX.
Hongda Huang, Zhong Deng, Olga Vladimirova, Andreas Wiedmer, Fang Lu, Paul M. Lieberman, Dinshaw J. Patel   +6 more
doaj   +1 more source

Gene expression cartography

Nature, 2019
This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature's AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections.
Mor Nitzan, Nikos Karaiskos, Nir Friedman, Nikolaus Rajewsky   +3 more
openaire   +4 more sources

Assessing Cognitive Functioning in Children With Brain Tumors: Interaction of Neighborhood Social Determinants of Health and Neurological Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background This study investigated how neighborhood‐level social determinants of health (SDOH), including redlining and neurological risk, interact to influence cognitive outcomes in children treated for brain tumors (CTBT). Methods A retrospective chart review of 161 CTBT aged 5–17 was conducted.
Alannah R. Srsich, Manali Zope, Peter M. Fantozzi, Cassie N. Kline, Iris Paltin, Matthew C. Hocking   +5 more
wiley   +1 more source

Ironing out the conflicts: iron supplementation reduces negatives bacterial interactions in the rhizosphere of an Atacama-endemic perennial grass

Environmental Microbiome
Background In plants, root exudates selectively influence the growth of bacteria that colonize the rhizosphere. Bacterial communities associated with root systems are involved in macro and micronutrients cycling and organic matter transformation.
Constanza Aguado-Norese, Jonathan E. Maldonado, Christian Hodar, Gabriel Galvez, Daniel E. Palma, Verónica Cambiazo, Mauricio Gonzalez   +6 more
doaj   +1 more source

Developmental regulation of expression of the lactate dehydrogenase (LDH) multigene family during mouse spermatogenesis [PDF]

, 1990
Expression of the Lactate Dehydrogenase (LDH) genes during various stages of spermatogenesis was studied by using a combination of Northern blot analyses and in situ hybridization techniques.
Bellvé, Anthony, Del Mazo, Jesus, Eversole, Pam, Hiraoka, Yukihiro, Li, Steven S. L., Simon, Melvin, Thomas, Kelwyn   +6 more
core  

The impact of sex on gene expression across human tissues

Science, 2020
Sex differences in the human transcriptome are widespread and tissue specific, and they contribute to complex traits. The role of sex in the human transcriptome In humans, the inheritance of the XX or XY set of sex chromosomes is responsible for most ...
Meritxell Oliva, Manuel Muñoz-Aguirre, Sarah Kim-Hellmuth, Valentin Wucher, Ariel D. H. Gewirtz, D. Cotter, P. Parsana, S. Kasela, B. Balliu, A. Viñuela, S. Castel, P. Mohammadi, F. Aguet, Yuxin Zou, E. Khramtsova, Andrew D. Skol, D. Garrido-Martín, F. Reverter, A. Brown, P. Evans, E. Gamazon, Anthony J. Payne, Rodrigo Bonazzola, A. Barbeira, Andrew R. Hamel, A. Martinez-Perez, J. Soria, B. Pierce, M. Stephens, E. Eskin, E. Dermitzakis, A. Segrè, H. Im, B. Engelhardt, K. Ardlie, S. Montgomery, A. Battle, T. Lappalainen, R. Guigó, B. Stranger   +39 more
semanticscholar   +1 more source