Results 181 to 190 of about 12,165,430 (302)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Gene expression profiling in DLBCL primary clinical samples

, 2016
Accession Number: GSE74266 Platform: GPL570: [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array Organism: Homo sapiens Published on 2016-10-05 Summary: Gene expression profiling was performed for 28 DLBCL primary clinical samples and assignment
Aalborg University Hospital, Dybkær, Karen; id_orcid, The Faculty of Engineering and Science (ENG), Klinik Kirurgi og Kræftbehandling, Department of Clinical Medicine, Schmitz, Alexander, Ettrup, Marianne Schmidt, Bilgrau, Anders Ellern, Klinik Diagnostik, Klinik Medicin, Bøgsted, Martin; id_orcid, Jørgensen, Laura Krogh, The Faculty of Medicine, Ranjbar, Benyamin, Aarhus University, Johnsen, Hans Erik, Primo, Maria Nascimento, Marques, Sara Correia, Department of Pathology, Blodsygdomme (Hæmatologi) [Klinik Medicin], Falgreen, Steffen, Laursen, Maria Bach, Bødker, Julie Støve; id_orcid, Mikkelsen, Jacob Giehm, Aalborg University, Department of Mathematical Sciences   +25 more
core  

In Silico Characterisation and Determination of Gene Expression Levels of the CPK Family Under Saline Stress Conditions in Chenopodium quinoa Willd. [PDF]

Int J Mol Sci
Lima-Huanca L, Alvarez-Vasquez A, Valderrama-Valencia M, Condori-Pacsi S.   +3 more
europepmc   +1 more source

Diverse environmental perturbations reveal the evolution and context-dependency of genetic effects on gene expression levels. [PDF]

Genome Res, 2022
Lea AJ, Peng J, Ayroles JF.
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Assessment of TSPO Gene Expression Levels in Colorectal Cancer Tumors: A Paired Sample Study. [PDF]

Cancer Rep (Hoboken)
Karami Gorji H, Karimi M, Mortezazadeh M, Shirsalimi N, Akhshabi S, Yousefi Ladmakhi A, Kashani M, Seyyed Mahmoudi ST, Mofidi A, Rezaei A.   +9 more
europepmc   +1 more source

Erratum to: Evaluation of gene expression levels in the diagnosis of lung adenocarcinoma and malignant pleural mesothelioma. [PDF]

Turk Gogus Kalp Damar Cerrahisi Derg, 2022
Ömeroğlu Şimşek G, Ağababaoğlu İ, Dursun D, Özekinci S, Erçetin P, Ellidokuz H, Aktaş S, Gürel D, Öztop İ, Akkoçlu A.   +9 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Evolutionary divergence of induced versus constitutive antiviral gene expression levels between primates and rodents. [PDF]

PLoS Comput Biol
Schneor L, Tussia-Cohen D, Fraimovitch E, Friedman S, Hagai T.   +4 more
europepmc   +1 more source

Analysis of ADORA2A, MTA1, PTGDS, PTGS2, NSF, and HNMT Gene Expression Levels in Peripheral Blood of Patients with Early Stages of Parkinson's Disease. [PDF]

Biomed Res Int, 2023
Semenova EI, Partevian SA, Shulskaya MV, Rudenok MM, Lukashevich MV, Baranova NM, Doronina OB, Doronina KS, Rosinskaya AV, Fedotova EY, Illarioshkin SN, Slominsky PA, Shadrina MI, Alieva AK.   +13 more
europepmc   +1 more source