Results 221 to 230 of about 7,080,207 (344)

Comparison of Discrimination Methods for the Classification of Tumors Using Gene Expression Data

, 2002
S. Dudoit, J. Fridlyand, T. Speed
semanticscholar   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Changes in gene expression levels caused by H3K9me3/H3K9ac modifications are associated with BmCPV infection in <i>Bombyx mori</i>. [PDF]

Virulence
Qiu Q, Tong X, Zhu M, Liu Z, Pang H, Li L, Feng Y, Hu X, Gong C.   +8 more
europepmc   +1 more source

KDmarkers: A biomarker database for investigating epigenetic methylation and gene expression levels in Kawasaki disease. [PDF]

Comput Struct Biotechnol J, 2022
Wu WS, Yang TH, Chen KD, Lin PH, Chen GR, Kuo HC.   +5 more
europepmc   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Association of Inflammasome Gene Expression Levels with Pathogenesis of Familial Mediterranean Fever in Armenians. [PDF]

Int J Mol Sci
Hayrapetyan V, Karapetyan L, Ghukasyan L, Atshemyan S, Ghazaryan H, Vardanyan V, Mukuchyan V, Arakelyan A, Zakharyan R.   +8 more
europepmc   +1 more source

Reference Gene U2 Enables Direct Comparison between Relative Gene Expression Levels of Vascular Smooth Muscle Cells in Tissue and Culture Using Real-Time Quantitative PCR. [PDF]

Cells, 2023
Rager C, Klöpper T, Pfeil U, Tasch S, Whittaker MR, Exintaris B, Mietens A, Middendorff R.   +7 more
europepmc   +1 more source

Gene expression levels.

, 2014
S. Chantal, J. Vicki, Dandekar Ravi, Durbin-Johnson Blythe, Charlet-Berguerand Nicolas, P. A. Bradley, R. Frank, A. Kathleen, J. Tony, T. Flora   +9 more
semanticscholar   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Construction of a deep learning-based predictive model to evaluate the influence of mechanical stretching stimuli on MMP-2 gene expression levels in fibroblasts. [PDF]

Biomed Eng Online
Xiao R, Zhou H, Shi Z, Huang R, Zhang Y, Li J.   +5 more
europepmc   +1 more source