Results 261 to 270 of about 3,483,446 (299)

Base composition and expression level of human genes

Gene, 2004
It is well known that the gene distribution is non-uniform in the human genome, reaching the highest concentration in the GC-rich isochores. Also the amino acid frequencies, and the hydrophobicity, of the corresponding encoded proteins are affected by the high GC level of the genes localized in the GC-rich isochores.
Stilianos, Arhondakis, Fabio, Auletta, Giuseppe, Torelli, Giuseppe, D'Onofrio   +3 more
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Levels of duplicate gene expression in armoured catfishes

Journal of Heredity, 1980
Species of armoured catfishes differ significantly in their cellular DNA content and chromosome number. Starch gel electrophoresis of isozymes was used to determine whether each of 16 enzyme loci was expressed in a single or duplicate state. The percent of enzyme loci exhibiting duplicate locus expression in Corydoras aeneus, Corydoras julii, Corydoras
R A, Dunham, D P, Philipp, G S, Whitt
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Gene-expression analysis at the single-cell level

Trends in Pharmacological Sciences, 2000
The manner in which a cell responds to and influences its environment is ultimately determined by the genes that it expresses. To fully understand and manipulate cellular function, identification of these expressed genes is essential. Techniques such as RT-PCR enable examination of gene expression at the tissue level.
A K, Dixon, P J, Richardson, R D, Pinnock, K, Lee   +3 more
openaire   +2 more sources

Discovering High-Order Patterns of Gene Expression Levels

Journal of Computational Biology, 2008
This paper reports the discovery of statistically significant association patterns of gene expression levels from microarray data. By association patterns, we mean certain gene expression intensity intervals having statistically significant associations among themselves and with the tissue classes, such as cancerous and normal tissues.
Andrew K C, Wong, Wai-Ho, Au, Keith C C, Chan   +2 more
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Decreased GADD45A gene expression level in MGUS

Pamukkale Medical Journal, 2023
Purpose: Monoclonal gammopathy of undetermined significance (MGUS) is a plasma cell dyscrasia. It is known that MGUS has an increased risk of progression to multiple myeloma (MM), and also prepares the ground for diseases such as Waldenstrom macroglobulinemia (WM), non-Hodgkin lymphoma, and chronic lymphocytic leukemia (CLL).
Ilknur SUER, Aynur DAĞLAR ADAY, Gözde ÖZTAN   +2 more
openaire   +1 more source

Inferring gene expression dynamics from reporter protein levels

Biotechnology Journal, 2008
AbstractWe present a mathematical method for inferring the dynamics of gene expression from time series of reporter protein assays and cell populations. We show that estimating temporal expression dynamics from direct visual inspection of reporter protein data is unreliable when the half‐life of the protein is comparable to the time scale of the ...
David, Brown, C Phoebe, Lostroh
openaire   +2 more sources

RNase Protection Assay for Quantifying Gene Expression Levels

2007
Quantifying the level of mRNA is central to the study of mammalian gene expression. Conventional approaches such as Northern blotting are often prone to low sensitivity and reproducibility. The RNase protection assay (RPA) provides a sensitive alternative for the detection and quantification of mRNA. The RPA is based on the hybridization in solution of
Yongxia, Qu, Mohamed, Boutjdir
openaire   +2 more sources

On DNA Computers Controlling Gene Expression Levels

Proceedings of the 44th IEEE Conference on Decision and Control, 2006
The area of bio-molecular computing has recently witnessed a major paradigm shift. Rather then being used only as simple calculating units capable of solving hard combinatorial or numerical problems, DNA computers are increasingly becoming more tailored to operate like intelligent ent biological machines with unprecedented potentials.
O. Milenkovic, N. Kashyap, B. Vasic
openaire   +1 more source

Thymic myoid cells express high levels of muscle genes

Journal of Neuroimmunology, 2004
To explore the possible contribution of thymic myoid cells in tolerance induction mechanisms, we quantified by real-time RT-PCR, the expression of 12 muscle genes (the five subunits of acetylcholine receptor, Musk, rapsyn, utrophin, ErbB2, ErbB3, troponin T, and MCK) in a human thymic myoid cell line (MITC), compared to thymic epithelial cells (TEC ...
Mesnard-Rouiller, Laurence, Bismuth, Jacky, Wakkach, Abdel, Poëa-Guyon, Sandrine, Berrih-Aknin, Sonia   +4 more
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PARP gene expression: control at many levels

Molecular and Biochemical Parasitology, 1998
H R, Hotz, S, Biebinger, J, Flaspohler, C, Clayton   +3 more
openaire   +2 more sources