Results 41 to 50 of about 7,080,207 (344)

Production of glycoprotein-deleted rabies viruses for monosynaptic tracing and high-level gene expression in neurons

open access: yesNature Protocols, 2010
Recombinant rabies viruses rendered replication-deficient by the deletion of their envelope glycoprotein gene are useful tools for neuroscientists, permitting (1) extraordinarily high transgene expression levels within neurons, (2) retrograde infection ...
Citation Wickersham   +3 more
semanticscholar   +1 more source

Identification of core genes associated with different phosphorus levels in quinoa seedlings by weighted gene co-expression network analysis

open access: yesBMC Genomics, 2023
Background Quinoa is a highly nutritious and novel crop that is resistant to various abiotic stresses. However, its growth and development is restricted due to its limited utilization of soil phosphorus.
Shan Zhang   +11 more
doaj   +1 more source

Exposure to Endocrine Disruptors and Nuclear Receptors Gene Expression in Infertile and Fertile Men from Italian Areas with Different Environmental Features [PDF]

open access: yes, 2015
Internal levels of selected endocrine disruptors (EDs) (i.e., perfluorooctane sulfonate (PFOS), perfluorooctanoic acid (PFOA), di-2-ethylhexyl-phthalate (DEHP), mono-(2-ethylhexyl)-phthalate (MEHP), and bisphenol A (BPA)) were analyzed in blood/serum of ...
Bergamasco B   +14 more
core   +2 more sources

Cloning with tandem gene systems for high level gene expression

open access: yesNucleic Acids Research, 1984
A method has been devised for increasing the copy number of a gene (or genes) cloned into a plasmid while minimizing the size of the plasmid. If n copies of a transcriptional unit are cloned, including the promoter, coding region and terminator, the size of the plasmid will increase by n times the total size of the unit.
N, Lee   +3 more
openaire   +3 more sources

Gene length and expression level shape genomic novelties [PDF]

open access: yesGenome Research, 2014
Gene duplication and alternative splicing are important mechanisms in the production of genomic novelties. Previous work has shown that a gene’s family size and the number of splice variants it produces are inversely related, although the underlying reason is not well understood.
Vladislav Grishkevich, Itai Yanai
openaire   +2 more sources

Methylation QTLs Are Associated with Coordinated Changes in Transcription Factor Binding, Histone Modifications, and Gene Expression Levels

open access: yesbioRxiv, 2014
DNA methylation is an important epigenetic regulator of gene expression. Recent studies have revealed widespread associations between genetic variation and methylation levels.
N. Banovich   +8 more
semanticscholar   +1 more source

Pax-8 protein levels regulate thyroglobulin gene expression [PDF]

open access: yesJournal of Molecular Endocrinology, 1998
Pax proteins are transcription factors that control differentiation of several cell types. In adult organisms Pax-8 is expressed in the follicular thyroid cell where it interacts with sequences of thyroglobulin and thyroperoxidase promoters.
FABBRO D   +4 more
openaire   +2 more sources

Molecular functional mechanisms of two alcohol acetyltransferases in Lavandula x intermedia (lavandin)

open access: yesFrontiers in Chemistry
Volatile esters are key flavor components in most plants, including Lavandula x intermedia (lavandin). The final step in ester biosynthesis is catalyzed by Lavandula x intermedia alcohol acyltransferases (LiAATases), which attach alcohols to acyl groups.
Dafeng Liu   +8 more
doaj   +1 more source

Gene Expression and Methylation Levels of PCSK9 Gene in Iraqi Patients with Coronary Artery Disease

open access: yesمجلة بغداد للعلوم, 2023
The expression of the Proprotein Convertase Subtilisin/Kexin Type 9 gene (PCSK9) is inextricably related to lipid levels and a risk of atherosclerotic coronary artery disease (ASCAD).
Marwa M. Al-Attar   +2 more
doaj   +1 more source

Applications of Little's Law to stochastic models of gene expression

open access: yes, 2010
The intrinsic stochasticity of gene expression can lead to large variations in protein levels across a population of cells. To explain this variability, different sources of mRNA fluctuations ('Poisson' and 'Telegraph' processes) have been proposed in ...
Elgart, Vlad   +2 more
core   +1 more source

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