Results 51 to 60 of about 7,080,207 (344)

A genomic analysis and transcriptomic atlas of gene expression in Psoroptes ovis reveals feeding- and stage-specific patterns of allergen expression [PDF]

, 2019
Background: Psoroptic mange, caused by infestation with the ectoparasitic mite, Psoroptes ovis, is highly contagious, resulting in intense pruritus and represents a major welfare and economic concern for the livestock industry Worldwide.
Bartley, Kathryn, Burgess, Stewart TG, Down, Rachel E, Dunn, Jackie, Marr, Edward J, Nisbet, Alasdair J, Nunn, Francesca G, Prickett, Jessica C, Rombauts, Stephane, Van de Peer, Yves, Van Leeuwen, Thomas, Weaver, Robert J   +11 more
core   +2 more sources

Association of MAPT haplotypes with Alzheimer’s disease risk and MAPT brain gene expression levels

Alzheimer's Research & Therapy, 2014
IntroductionMAPT encodes for tau, the predominant component of neurofibrillary tangles that are neuropathological hallmarks of Alzheimer’s disease (AD).
M. Allen, Michaela Kachadoorian, Zachary S. Quicksall, F. Zou, H. Chai, C. Younkin, J. Crook, V. Pankratz, M. Carrasquillo, Siddharth Krishnan, Thuy Nguyen, Li Ma, Kimberly G. Malphrus, S. Lincoln, G. Bisceglio, C. Kolbert, J. Jen, Shubhabrata Mukherjee, J. Kauwe, P. Crane, J. Haines, R. Mayeux, M. Pericak-Vance, L. Farrer, G. Schellenberg, J. Parisi, R. Petersen, N. Graff-Radford, D. Dickson, S. Younkin, N. Ertekin-Taner   +30 more
semanticscholar   +1 more source

Structural and functional insights into NAD(P)H-quinone oxidoreductases in lavender: implications for abiotic stress tolerance and essential oil production

Frontiers in Plant Science
Lavender essential oils (EOs) are economically valuable, with biosynthesis linked to photosynthesis. NAD(P)H-quinone oxidoreductases (NDHs) play a crucial role in regulating photosynthetic processes.
Dafeng Liu, Na Li, Huashui Deng, Daoqi Song, Minawaier Maimaiti, Ayidana Nuerbieke, Mingtai Yekepeng, Kailibinuer Aili   +7 more
doaj   +1 more source

Mitochondrial impairment increases FL-PINK1 levels by calcium-dependent gene expression

Neurobiology of Disease, 2014
Mutations of the PTEN-induced kinase 1 (PINK1) gene are a cause of autosomal recessive Parkinson's disease (PD). This gene encodes a mitochondrial serine/threonine kinase, which is partly localized to mitochondria, and has been shown to play a role in ...
Rubén Gómez-Sánchez, Matthew E. Gegg, José M. Bravo-San Pedro, Mireia Niso-Santano, Lydia Alvarez-Erviti, Elisa Pizarro-Estrella, Yolanda Gutiérrez-Martín, Alberto Alvarez-Barrientos, José M. Fuentes, Rosa Ana González-Polo, Anthony H.V. Schapira   +10 more
doaj   +1 more source

Whole blood gene expression and interleukin-6 levels

Genomics, 2014
Circulating interleukin-6 levels increase with advancing age and are a risk factor for various diseases and mortality. The characterization of gene expression profiles associated with interleukin-6 levels might suggest important molecular events underlying its regulation.We studied the association of transcriptional profiles with interleukin-6 levels ...
Lin, H, Joehanes, R, Pilling, LC, Dupuis, J, Lunetta, KL, Ying, SX, Benjamin, EJ, Hernandez, Dena, Singleton, A, Melzer, D, Munson, PJ, Levy, D, Ferrucci, L, Murabito, JM   +13 more
openaire   +3 more sources

Transcript‐level expression control of plant NLR genes [PDF]

Molecular Plant Pathology, 2017
Summary Plant NLR genes encode sensitive immune receptors that can mediate the specific recognition of pathogen avirulence effectors and activate a strong defence response, termed effector‐triggered immunity. The expression of NLRs requires strict regulation, as their ability to trigger immunity is dependent on their dose, and ...
Lai, Yan, Eulgem, Thomas
openaire   +4 more sources

Nonlinear Dynamics in Gene Regulation Promote Robustness and Evolvability of Gene Expression Levels.

PLoS ONE, 2016
Cellular phenotypes underpinned by regulatory networks need to respond to evolutionary pressures to allow adaptation, but at the same time be robust to perturbations.
Arno Steinacher, Declan G Bates, Ozgur E Akman, Orkun S Soyer   +3 more
doaj   +1 more source

Autism and increased paternal age related changes in global levels of gene expression regulation. [PDF]

PLoS ONE, 2011
A causal role of mutations in multiple general transcription factors in neurodevelopmental disorders including autism suggested that alterations in global levels of gene expression regulation might also relate to disease risk in sporadic cases of autism.
Mark D Alter, Rutwik Kharkar, Keri E Ramsey, David W Craig, Raun D Melmed, Theresa A Grebe, R Curtis Bay, Sharman Ober-Reynolds, Janet Kirwan, Josh J Jones, J Blake Turner, Rene Hen, Dietrich A Stephan   +12 more
doaj   +1 more source

Functional and Mechanistic Insights into the Fatty-Acid CoA Ligase FadK in Escherichia coli

Frontiers in Bioscience-Landmark
Background: Escherichia coli (E. coli) is a common opportunistic bacterial pathogen in both human and animal populations. Fatty acids serve as the central carbon and energy source, a process mediated by fatty acid-coenzyme A (CoA ...
Dafeng Liu, Ablikim Abdiriyim, Lvxia Zhang, Feng Yu   +3 more
doaj   +1 more source

Gene expression levels of inflammatory mediators in diabetic foot ulcer patients

مجلة مركز بحوث التقنيات الاحيائية, 2023
 Background: Diabetic foot ulcer (DFU) is a common serious complication of diabetes. Nowadays there is a suggestion that referred to the fact the chronicity of DFU is a result of the positive feedback of proinflammatory cytokines production ...
Israa K. Hussein, Wafaa S. Shani
doaj   +1 more source