Results 71 to 80 of about 3,483,446 (299)

Effects of Flight on Gene Expression and Aging in the Honey Bee Brain and Flight Muscle [PDF]

, 2012
Honey bees move through a series of in-hive tasks (e.g., “nursing”) to outside tasks (e.g., “foraging”) that are coincident with physiological changes and higher levels of metabolic activity.
Ammons, Andrew, Benito, Azucena A., Elekonich, Michelle M., Mancinelli, Georgina E., Margotta, Joseph, Roberts, Stephen P.   +5 more
core   +5 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Ameliorative effects of strigolactone on tolerance to lead stress on lettuce (Lactuca sativa L.) plants

Scientific Reports
Soil contamination by heavy metals, particularly lead (Pb), which is considered the second most toxic metal, poses serious risks to plants and humans due to its accumulation from various anthropogenic activities. Strigolactones (SLs) are a novel class of
Sumeyra Ucar, Merve Yuce, Esma Yigider, Murat Aydin, Metin Turan, Melek Ekinci, Emre Ilhan, Ayse Gul Kasapoglu, Melike Akca, Firuze Oztemiz, Guleray Agar, Ertan Yildirim   +11 more
doaj   +1 more source

Gene Expression Profile Changes After Short-activating RNA-mediated Induction of Endogenous Pluripotency Factors in Human Mesenchymal Stem Cells [PDF]

, 2012
It is now recognized that small noncoding RNA sequences have the ability to mediate transcriptional activation of specific target genes in human cells.
Alluin, J, Habib, N, Kasahara, N, Mintz, P, Rossi, J, Sun, G, Sætrom, P, Voutila, J   +7 more
core   +4 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Addendum: Precise tuning of gene expression levels in mammalian cells

Nature Communications, 2019
Following re-sequencing of the miSFIT constructs used in the paper, two of the construct variants inserted into the 3’UTR of PD-1, namely ‘12C’ and ‘17A, 18G’, have been found to contain additional insertions not present in the other construct variants ...
Yale S. Michaels, Mike B. Barnkob, Hector Barbosa, Toni A. Baeumler, Mary K. Thompson, Violaine Andre, Huw Colin-York, Marco Fritzsche, Uzi Gileadi, Hilary M. Sheppard, David J. H. F. Knapp, Thomas A. Milne, Vincenzo Cerundolo, Tudor A. Fulga   +13 more
doaj   +1 more source

Manipulating the Prion Protein Gene Sequence and Expression Levels with CRISPR/Cas9. [PDF]

PLoS ONE, 2016
The mammalian prion protein (PrP, encoded by Prnp) is most infamous for its central role in prion diseases, invariably fatal neurodegenerative diseases affecting humans, food animals, and animals in the wild.
Lech Kaczmarczyk, Ylva Mende, Branko Zevnik, Walker S Jackson   +3 more
doaj   +1 more source

Expression of SMARCD1 interacts with age in association with asthma control on inhaled corticosteroid therapy. [PDF]

, 2020
BackgroundGlobal gene expression levels are known to be highly dependent upon gross demographic features including age, yet identification of age-related genomic indicators has yet to be comprehensively undertaken in a disease and treatment-specific ...
Burchard, Esteban G, Croteau-Chonka, Damien C, Dahlin, Amber, Eng, Celeste, Kelly, Rachel, Kho, Alvin T, Lu, Quan, Lutz, Sharon M, Mak, Angel CY, McGeachie, Michael J, Oh, Sam S, Panganiban, Ronald, Raby, Benjamin A, Rodriguez-Santana, Jose R, Saef, Benjamin, Sajuthi, Satria, Seibold, Max A, Sordillo, Joanne E, Tantisira, Kelan G, Urbanek, Cydney, Wang, Alberta L, Weiss, Scott T, Wu, Ann Chen   +22 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Gene amplification as a form of population-level gene expression regulation

Nature Ecology & Evolution, 2020
Organisms cope with change by taking advantage of transcriptional regulators. However, when faced with rare environments, the evolution of transcriptional regulators and their promoters may be too slow. Here, we investigate whether the intrinsic instability of gene duplication and amplification provides a generic alternative to canonical gene ...
I. Tomanek, R. Grah, M. Lagator, A. M. C. Andersson, J. P. Bollback, G. Tkačik, C. C. Guet   +6 more
openaire   +4 more sources