Results 231 to 240 of about 2,789,846 (387)

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

Molecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson, Andrew Bakshi, Andrew Ryan, Heather Thorne, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Roxanne Toivanen, David L. Goode   +12 more
wiley   +1 more source

Host-Virus Interface in Persistent SARS-CoV-2 Infections: Viral Characteristic Evolution and Gene Expression Profiling Analysis. [PDF]

Int J Mol Sci
Maarif AS, Nishikawa Y, Takata M, Kanai K, Riyandani E, Mukuda K, Mimura M, Yamaguchi K, Kato H, Okamoto R, Okada K, Kitaura T, Nakamoto M, Yamasaki A, Kageyama S, Chikumi H.   +15 more
europepmc   +1 more source

Gene Expression Profiling of Human Stent-Induced Neointima by cDNA Array Analysis of Microscopic Specimens Retrieved by Helix Cutter Atherectomy [PDF]

, 2001
Dietlind Zohlnhöfer, Christoph A. Klein, Thomas Richter, Richard Brandl, Alexander Murr, Thomas Nührenberg, Albert Schömig, Patrick A. Baeuerle, Franz–Josef Neumann   +8 more
openalex   +1 more source

Molecular diagnosis of eosinophilic esophagitis by gene expression profiling.

Gastroenterology, 2013
T. Wen, E. Stucke, Tommie M. Grotjan, Katherine A. Kemme, J. Abonia, P. Putnam, J. Franciosi, J. Garza, A. Kaul, Eileen C. King, M. Collins, J. Kushner, M. Rothenberg   +12 more
semanticscholar   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Gene expression profiling for the diagnosis of male breast cancer. [PDF]

BMC Cancer
Liu J, Sun Y, Qi P, Wo Y, Pang Y, Xu Q, Xu M, Huang S, Wang Q.   +8 more
europepmc   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Spatial gene expression profiling identifies prognostic features of residual tumors after neoadjuvant chemotherapy in triple-negative breast cancer. [PDF]

Front Oncol
Won HS, Kim YS, Seo KJ, Jun SY, Sun S, Choi M, Yoon JS, Byun JH.   +7 more
europepmc   +1 more source

Diagnosis of multiple cancer types by shrunken centroids of gene expression

Proceedings of the National Academy of Sciences of the United States of America, 2002
R. Tibshirani, T. Hastie, B. Narasimhan, Gilbert Chu   +3 more
semanticscholar   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source