The CRISPR-dCas9 interference system suppresses inhA gene expression in Mycobacterium smegmatis
CRISPR-dead Cas9 interference (CRISPRi) has become a valuable tool for precise gene regulation. In this study, CRISPRi was designed to target the inhA gene of Mycobacterium smegmatis (Msm), a gene necessary for mycolic acid synthesis.
Nuntita Singpanomchai+1 more
doaj +1 more source
Unveiling the orchestration: mycobacterial small RNAs as key mediators in host-pathogen interactions
Small RNA (sRNA) molecules, a class of non-coding RNAs, have emerged as pivotal players in the regulation of gene expression and cellular processes.
Rajni Garg+2 more
doaj +1 more source
Dickeya dadantii is a bacterial pathogen that causes soft rot disease in many plant species worldwide, including temperate, subtropical, and tropical regions. This bacterium employs the type III secretion system (T3SS) to manipulate host immune responses.
Alaleh Ghasemi+2 more
doaj +1 more source
Abstract Genomic mutations allow bacteria to adapt rapidly to adverse stress environments. The three-dimensional conformation of the genome may also play an important role in transcriptional regulation and environmental adaptation. Here, using chromosome conformation capture, we investigate the high-order architecture of the Zymomonas ...
Mao Chen+10 more
openaire +2 more sources
Regulation of Bacterial Gene Expression by Metals
David J. Westenberg, Mary Lou Guerinot
openaire +3 more sources
Regulation of bacterial virulence gene expression by the host environment. [PDF]
openaire +3 more sources
Transcriptomic profiling reveals RetS-mediated regulation of type VI secretion system and host cell responses in <i>Pseudomonas aeruginosa</i> infections. [PDF]
Wu Y+9 more
europepmc +1 more source
Mycobacterium tuberculosis curli pili (MTP) and heparin-binding hemagglutinin adhesin (HBHA) facilitate regulation of central carbon metabolism, enhancement of ATP synthesis and cell wall biosynthesis. [PDF]
Naidoo TJ+4 more
europepmc +1 more source
Delayed Chlorosis in Arabidopsis Ecotype Dijon-G During Bacterial Infection and Dark-Induced Senescence. [PDF]
Lee YH+4 more
europepmc +1 more source
Activation of <i>BmToll9-1</i> in Silkworm (<i>Bombyx mori</i>) Larval Midgut by <i>Escherichia coli</i> and Regulation of Growth. [PDF]
Liu J, Chen W, Lai M, Chen J, Swevers L.
europepmc +1 more source