Results 151 to 160 of about 381,546 (267)

Characterization of an AsnC/Lrp-family transcriptional regulator in <i>Herbaspirillum rubrisubalbicans</i> M1: linking plant interaction, nitrogen response and PHB metabolism. [PDF]

Front Microbiol
Chaves RBR, Alves LPS, de Lima Nichio BT, Tuleski TR, Baura VA, Muller-Santos M, Tomazini E, Sampaio A, Souza EM, Monteiro RA.   +9 more
europepmc   +1 more source

Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis

Advanced Science, EarlyView.
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu, Miaozhan Zou, Yunshang Bai, Yang He, Zhihao Jin, Baozhi Yang, Jinjin Du, Pei Ouyang, Yuanyuan Cai, Yuheng Zhang, Bingying Du, Chengcheng Ge, Jian‐an Gong, Xiaoyu Li, Yuanyi Zheng, Jing Ding, Bo Peng, Yanxia Rao   +17 more
wiley   +1 more source

Intestinal motility shapes spatiotemporal patterns of enterohemorrhagic <i>Escherichia coli</i> colonization and virulence gene expression in the host gut. [PDF]

Infect Immun
Dutta S, Galdamez W, Nguyen AT, Odem MA, Thompson L, Bosserman RE, Krachler AM.   +6 more
europepmc   +1 more source

IL‐7R‐Enriched Extracellular Vesicles From the Thymus Drive Colitis via Promoting Neutrophil Extracellular Trap Formation

Advanced Science, EarlyView.
Inflammatory bowel disease (IBD) pathogenesis remains unclear. This study reveals that thymus‐originated IL‐7R‐enriched extracellular vesicles exacerbate colitis by promoting neutrophil extracellular traps via a thymus‐gut axis, uncovering an inter‐organ communication mechanism in inflammatory bowel disease pathogenesis.
Yao Liao, Yuheng Liu, Ruibing Yang, Zifeng Zhu, Junwei Wu, Dinghao Li, Jin Su, Yingxin He, Shiqi Luo, Feiyang Cao, Haiyi Deng, Lanmengxi Yang, Ling Zhong, Peiying Peng, Xinyi Wu, Chunmei Cai, Zhen Li, Yujin Wu, Shuofeng Zhu, Jie Wei, Yi Yang, Lifu Wang   +21 more
wiley   +1 more source

Transposase-Associated Variation near <i>tnaA</i> in <i>Porphyromonas gingivalis</i> Is Linked to Indole Production and Virulence-Associated Gene Expression. [PDF]

Pathogens
Wei L, Xie C, Ren Q, Zhi M, Shen S, Gu X, Feng Q, Sun T.   +7 more
europepmc   +1 more source

Transcription Factor Promiscuity Drives Regulatory Rewiring and Evolvability in Gene Networks in Bacteria

Advanced Science, EarlyView.
When a master transcription factor (TF) is lost, bacteria can rapidly rewire gene regulatory networks by co‐opting related regulators. Using experimental evolution in Pseudomonas fluorescens, we show that TF promiscuity (low‐level, non‐cognate binding) provides the raw material for rewiring. Successful co‐option follows a predictable hierarchy governed
Tiffany B. Taylor, Alan M. Rice
wiley   +1 more source

Characterization of resistance to bacterial panicle blight in rice revealed by transcriptome and QTL mapping analyses. [PDF]

Front Plant Sci
Ontoy J, Bruno J, Shrestha B, Ham JH.
europepmc   +1 more source

Redox‐Dependent Chaperoning of GBF1 Condensates Regulates Seed Germination in Arabidopsis

Advanced Science, EarlyView.
In dormant seeds (low ROS), GBF1 forms liquid condensates to repress the germination gene CathB3, and the chaperone GIP1 maintains condensate liquidity and repressive activity. Upon imbibition (high ROS), ROS oxidize GIP1 during germination, impairing its chaperone function.
Yunying Wang, Xiaofeng Fang
wiley   +1 more source

Synthetic Toll‐Like Receptors for Control of Innate Immunity With Far‐Red Light

Advanced Science, EarlyView.
Synthetic Toll‐like receptors (TLRs) are engineered by replacing their natural sensing regions with a far‐red‐light‐responsive module from a bacterial phytochrome. These synthetic receptors enable light‐controlled regulation of immune signaling in mammalian cells.
Anna V. Leopold, Vladislav V. Verkhusha
wiley   +1 more source

Comparative Effects of <i>Escherichia coli</i> vs. <i>Porphyromonas gingivalis</i> Lipopolysaccharides on Osteogenic Differentiation and the Expression of lncRNAs in Periodontal Ligament Stem Cells. [PDF]

Int J Mol Sci
Suciu TS, Bran S, Berindan-Neagoe I, Raduly L, Zanoaga O, Budisan L, Nutu A, Soritau O, Strilciuc S, Leucuța D, Feștilă D, Almășan O, Aghiorghiesei AI, Băciuț M.   +13 more
europepmc   +1 more source