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Regulation of Bacterial Gene Expression

1989
The total properties of any bacterium result from an interplay between its genome and its environment. The bacterium Escherichia coli carries approximately 3000 genes, but this total repertoire describes its potential properties and, in reality, only a small subset of this genetic information is expressed at any given moment. A primary influence of the
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Regulation of bacterial gene expression by metal–protein complexes

Molecular Microbiology, 1990
SummaryMetal ions are essential cofactors in several transacting bacterial gene regulators. Upon binding of the metal, the receptor proteins act either as repressors of gene expression or, in other systems, as transcriptional activators. Other metal‐dependent regulatory proteins may function, directly or indirectly, as sensors of the cellular oxygen ...
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Bacterial expression system with tightly regulated gene expression and plasmid copy number

Gene, 2004
A new Escherichia coli host/vector system has been engineered to allow tight and uniform modulation of gene expression and gamma origin (ori) plasmid copy number. Regulation of gamma ori plasmid copy number is achieved through arabinose-inducible expression of the necessary Rep protein, pi, whose gene was integrated into the chromosome of the host ...
Lisa M, Bowers   +4 more
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DNA Supercoiling as a Regulator of Bacterial Gene Expression

1987
Studies of gene expression have advanced to a stage at which we can ask quite detailed questions about the factors that influence transcription and the ways in which these factors interact with each other. Such factors include not only the specific proteins that bind to regulatory sites on DNA, but also more subtle aspects of DNA structure, such as ...
Martin Gellert, Rolf Menzel
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Regulation of Bacterial Gene Expression by Protease-Alleviated Spatial Sequestration (PASS)

ACS Synthetic Biology, 2015
In natural microbial systems, conditional spatial sequestration of transcription factors enables cells to respond rapidly to changes in their environment or intracellular state by releasing presynthesized regulatory proteins. Although such a mechanism may be useful for engineering synthetic biology technologies ranging from cell-based biosensors to ...
Ragan A, Pitner   +2 more
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Bacterial lipases from Pseudomonas: Regulation of gene expression and mechanisms of secretion

Biochimie, 2000
Lipases from Pseudomonas bacteria are widely used for a variety of biotechnological applications. Overexpression in heterologous hosts like Escherichia coli failed to produce enzymatically active lipase prompting to study the molecular mechanisms underlying the regulation of lipase gene expression and secretion. The prototype lipase from P.
F, Rosenau, K, Jaeger
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Regulation of Expression of Bacterial Genes in the Absence of Active Cell Growth

Russian Journal of Genetics, 2005
Global changes in cell physiology and metabolism take place in bacterial cells entering the stationary phase. The processes that ensure cell survival under adverse environmental conditions are activated, and cells with an improved resistance to many stress factors are formed as a result of the general stress response. The review considers the molecular
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The role of mRNA degradation in the regulated expression of bacterial photosynthesis genes

Molecular Microbiology, 1993
SummaryRegulation of gene expression in bacteria, as in eukaryotic cells, is often achieved by variation of mRNA levels. Since the steady state levels of mRNA depend on both the rate of synthesis and the rate of decay, both mechanisms are important for gene regulation. After considerable effort undertaken over many years to understand the regulation of
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Bacterial Aminoacyl-tRNA Synthetases: Genes and Regulation of Expression

2014
Aminoacyl-tRNA synthetases (AARS) form a class of essential enzymes whose main role is to ligate amino acids to tRNAs. This chapter reviews what is known about the AARS genes, their chromosomal localization, their organization, and the regulation of their expression.
Harald Putzer   +2 more
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Regulation of gene expression in mouse macrophages stimulated with bacterial CpG-DNA and lipopolysaccharide

Journal of Leukocyte Biology, 2002
Abstract CpG-DNA is known as a potent immunostimulating agent and may contribute in therapeutic treatment of many immune disorders. CpG-DNA triggers innate and acquired immune responses through activated expression of various genes in immune cells, including macrophages.
Jian Jun, Gao   +6 more
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