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Regulation of Bacterial Gene Expression by Protease-Alleviated Spatial Sequestration (PASS)

ACS Synthetic Biology, 2015
In natural microbial systems, conditional spatial sequestration of transcription factors enables cells to respond rapidly to changes in their environment or intracellular state by releasing presynthesized regulatory proteins. Although such a mechanism may be useful for engineering synthetic biology technologies ranging from cell-based biosensors to ...
Andrew Scarpelli   +2 more
openaire   +3 more sources

The use of RNAs complementary to specific mRNAs to regulate the expression of individual bacterial genes [PDF]

open access: possibleCell, 1984
A naturally occurring small RNA molecule ( micF RNA), complementary to the region encompassing the Shine-Dalgarno sequence and initiation codon of the ompF mRNA, is known to block the expression of that mRNA in E. coli. We have constructed a plasmid that produces a complementary RNA to the E. coli lpp mRNA (mic[Ipp] RNA). Induction of the mic(Ipp) gene
Masayori Inouye   +2 more
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Bacterial Aminoacyl-tRNA Synthetases: Genes and Regulation of Expression

2014
Aminoacyl-tRNA synthetases (AARS) form a class of essential enzymes whose main role is to ligate amino acids to tRNAs. This chapter reviews what is known about the AARS genes, their chromosomal localization, their organization, and the regulation of their expression.
Mathias Springer   +2 more
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The role of mRNA degradation in the regulated expression of bacterial photosynthesis genes

Molecular Microbiology, 1993
SummaryRegulation of gene expression in bacteria, as in eukaryotic cells, is often achieved by variation of mRNA levels. Since the steady state levels of mRNA depend on both the rate of synthesis and the rate of decay, both mechanisms are important for gene regulation. After considerable effort undertaken over many years to understand the regulation of
openaire   +3 more sources

Search for Alternative RNA Secondary Structures Regulating Expression of Bacterial Genes

Molecular Biology, 2003
Expression of many bacterial genes is regulated by formation of alternative secondary RNA structure within the leader mRNA sequence. Our algorithm designed to search for these structures (basing on analysis of one nucleotide sequence) was applied to analyze operons of amino acid biosynthesis in alpha- and gamma-proteobacteria.
L. A. Leont'ev   +3 more
openaire   +2 more sources

Regulation of Expression of Bacterial Genes in the Absence of Active Cell Growth

Russian Journal of Genetics, 2005
Global changes in cell physiology and metabolism take place in bacterial cells entering the stationary phase. The processes that ensure cell survival under adverse environmental conditions are activated, and cells with an improved resistance to many stress factors are formed as a result of the general stress response. The review considers the molecular
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Bacterial Growth Rate And The Metabolic Regulation Of Gene Expression.

1977
PhD ; Microbiology ; University of Michigan, Horace H. Rackham School of Graduate Studies ; http://deepblue.lib.umich.edu/bitstream/2027.42/189944/2/7723531 ...
openaire   +2 more sources

Cancer epigenetics in clinical practice

Ca-A Cancer Journal for Clinicians, 2023
Veronica Davalos, Manel Esteller
exaly  

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