Results 111 to 120 of about 7,339,069 (294)
Conditional circadian regulation of PHYTOCHROME A gene expression [PDF]
, 2001 The phytochrome photoreceptors and the circadian clock control many of the same developmental processes, in all organs and throughout the growth of Arabidopsis plants. Phytochrome A (phyA) provides light input signals to entrain the circadian clock.
Nagy, F +4 more
core +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Poultry ScienceThis study examined the developmental and genotype dependent expression of key myogenic (MYOD1, MYOG, PAX7), growth related (IGF1, GHR, MSTN), mitochondrial (ANT, COXIII, UCP), and antioxidant (SOD1, CAT) genes in skeletal muscles of Japanese quail ...
Gonca Sonmez +3 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Communications BiologyHolometabolous insects undergo complex phenotypic changes during development in four major stages: egg, larva, pupa and adult. Such changes are typically driven by strong transcriptome and proteome dynamics, making this process an excellent system for ...
Maya Wilkens +7 more
doaj +1 more source
Frontiers in Cell and Developmental BiologyUnderstanding embryonic patterning, the process by which groups of cells are partitioned into distinct identities defined by gene expression, is a central challenge in developmental biology.
Jimena Garcia-Guillen, Ezzat El-Sherif
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Sterol gene expression in Arabidopsis [PDF]
, 2009 Sterols are recognized as playing vital roles in plant development, as has been demonstrated from mutational studies. The study of the hydra mutants of Arabidopsis provides new tools to dissect sterol function in development at the molecular genetic ...
Liu, Dongbin
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source