Drug Screening of Primary Human Endometriotic Cells Based on Micro‐Encapsulating Microfluidic Chip
To address the challenges of unclear mechanisms and poor therapeutic efficacy in endometriosis (EMs), this study develops a microfluidic chip platform integrated with primary cell‐laden microcapsules. Gradient drug screening reveals individualized treatment response variations among patients and their correlation with clinical outcomes.
Qiong Chen+5 more
wiley +1 more source
BackgroundThe functions, actions, and regulation of tissue metabolism affected by the consumption of long chain polyunsaturated fatty acids (LC-PUFA) from fish oil and other sources remain poorly understood; particularly how LC-PUFAs affect transcription
A. Berger+3 more
semanticscholar +1 more source
This study illustrates the impact of viruses on carbon cycling in soils with different availabilities of carbon. In conditions of low carbon availability, viruses adopt a lysogenic lifestyle, integrate into the host genomes and facilitate the degradation of carbon.
Mingfeng Liu+8 more
wiley +1 more source
Comparative transcriptomic analysis unveils interactions between the regulatory CarS protein and light response in Fusarium [PDF]
Background The orange pigmentation of the agar cultures of many Fusarium species is due to the production of carotenoids, terpenoid pigments whose synthesis is stimulated by light.
Limón Mirón, María del Carmen+5 more
core +1 more source
Cryptococcus neoformans is an opportunistic human fungal pathogen, but its infection is militated by phagocytosis and phagolysosomes in the host immune system. It has been reported that the pH of phagolysosomes containing C. neoformans is approximately 5.3.
Donghyeun Kim, Jung, Won Hee
openaire +1 more source
Electronic Nanomaterials for Plants: A Review on Current Advances and Future Prospects
Global food security faces mounting challenges from climate change and rapid population growth. This review highlights the pivotal role of electronic nanomaterials–including metals, metal oxides, and carbon‐based structures–in enhancing plant photosynthesis, nutrient uptake, and stress resilience. Furthermore, it explores how emerging platforms such as
Ciro Allará+8 more
wiley +1 more source
Dynamics of gene expression under feedback [PDF]
Gene expression is a stochastic process governed by the presence of specific transcription factors. Here we study the dynamics of gene expression in the presence of feedback, where a gene regulates its own expression. The nonlinear coupling between input and output of gene expression can generate a dynamics different from simple scenarios such as the ...
arxiv
Hydrogel‐Based Smart Materials for Wound Healing and Sensing
The graphical abstract illustrates the role of hydrogel‐based flexible materials in advancing biomedical applications, including wound healing, point‐of‐care diagnostics, smart patches, and wearable devices. Hydrogels are particularly promising in modern wound care due to their high‐water content, flexibility, and biocompatibility.
Thi Kim Ngan Duong+11 more
wiley +1 more source
Novel Genes of Fusarium graminearum That Negatively Regulate Deoxynivalenol Production and Virulence
Fusarium head blight of wheat, caused by Fusarium graminearum, is a serious disease resulting in both reduced yields and contamination of grain with trichothecene toxins, with severe consequences for mammalian health. Recently, we have identified several
Donald M. Gardiner+2 more
doaj +1 more source
Construction of a novel fungal gus expression plasmid, and its evaluation in Aspergillus nidulans : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Genetics at Massey University [PDF]
A GUS expression plasmid, pFunGus, was constructed containing a multi-cloning site for the insertion of gene regulatory elements, to be used in fungal reporter gene studies.
McGowan, Tania Louise
core