Results 91 to 100 of about 1,031,970 (204)
NKG2D and its ligands: one for all, all for one [PDF]
, 2018 The activating receptor NKG2D is peculiar in its capability to bind to numerous and highly diversified MHC class I-like self-molecules. These ligands are poorly expressed on normal cells but can be induced on damaged, transformed or infected cells, with ...
Cerboni, Cristina +7 more
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E2F1 activation is responsible for pituitary adenomas induced by HMGA2 gene overexpression
Cell Division, 2006 The High Mobility Group protein HMGA2 is a nuclear architectural factor that plays a critical role in a wide range of biological processes including regulation of gene expression, embryogenesis and neoplastic transformation. Several studies are trying to
Fusco Alfredo +3 more
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Emerging roles of telomeric chromatin alterations in cancer [PDF]
, 2019 Telomeres, the nucleoprotein structures that cap the ends of eukaryotic chromosomes, play important and multiple roles in tumorigenesis. Functional telomeres need the establishment of a protective chromatin structure based on the interplay between the ...
Biroccio, Annamaria +2 more
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Oncogenic reg IV is a novel prognostic marker for glioma patient survival
Diagnostic Pathology, 2012 Aim The aberrant expression of regenerating islet-derived family member, 4 (Reg IV) has been found in various human cancers. However, the roles of Reg IV gene and its encoding product in human glioma have not been clearly understood.
Wang Qi +7 more
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A preclinical model for the ATLL lymphoma subtype with insights into the role of microenvironment in HTLV-1-mediated lymphomagenesis [PDF]
, 2018 \uef7f View references (83) Adult T cell Leukemia/Lymphoma (ATLL) is a mature T cell malignancy associated with Human T cell Leukemia Virus type 1 (HTLV-1) infection.
Adriana Mattiolo +8 more
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BMC Genomics, 2009 Background Cells transformed by human adenoviruses (Ad) exhibit differential capacities to induce tumours in immunocompetent rodents; for example, Ad12-transformed rodent cells are oncogenic whereas Ad5-transformed cells are not.
Kellam Paul +3 more
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Diverse functional roles of miR-128-3p in human diseases: Focus on its roles in human cancer
Genes and DiseasesThe microRNA known as miR-128-3p demonstrates widespread tissue-specific expression with its genetic locus situated on human chromosome 2 (2q21.3), and is a multifunctional regulator with tissue-specific expression patterns that critically influences ...
Lingzi Zheng +6 more
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miR-126 and miR-126*: New Players in Cancer
The Scientific World Journal, 2010 Cancer progression is characterized by autarky in growth signals, insensitivity to growth-restrictive signals, evasion of apoptosis, a limitless potential to replicate, sustained angiogenesis, and tissue invasion, including metastasis.
Jeannette Meister, Mirko H. H. Schmidt
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The pathologists’ eyes on foregut: histopathological relations in the experimental and routine diagnostics [PDF]
, 2011 SUMMARY I. The study aimed to investigate the incidence of duodeno-gastroesophageal reflux-induced malignoma formation in a series of duodeno-esophageal anastomosis operations in rats.
Németh István Balázs
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