Results 111 to 120 of about 267,816 (318)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Identification of Co-Expression Modules of Cotton Plant Height-Related Genes Based on Weighted Gene Co-Expression Network Analysis

Agronomy
Plant height (PH) is a vital agronomic trait that significantly affects cotton yield and facilitates mechanized harvesting. Gaining insights into the genetic regulatory mechanisms governing plant height is fundamental to advancing cotton breeding.
Qian Huang, Li Liu, Hang Li, Xuwen Wang, Aijun Si, Liangrong He, Yu Yu   +6 more
doaj   +1 more source

Global Methylomic and Transcriptomic Analyses Reveal the Broad Participation of DNA Methylation in Daily Gene Expression Regulation of Populus trichocarpa

Frontiers in Plant Science, 2019
Changes in DNA methylation patterns in different tissues, at various developmental stages, and under environmental stimuli have been investigated in plants.
Lixiong Liang, Lixiong Liang, Yingying Chang, Yingying Chang, Junqian Lu, Junqian Lu, Xiaojuan Wu, Xiaojuan Wu, Qi Liu, Qi Liu, Weixi Zhang, Weixi Zhang, Xiaohua Su, Xiaohua Su, Bingyu Zhang, Bingyu Zhang   +15 more
doaj   +1 more source

Transcriptional and post-transcriptional regulation of gene expression in plants [PDF]

, 1992
In the past few years virtually every aspect of plant gene expression has been covered by thoughtful, in-depth reviews. In this article, it is not my goal to repeat, combine or update those reviews.
Kuhlemeier, Cris
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

EjGASA6 promotes flowering and root elongation by enhancing gibberellin biosynthesis

Journal of Integrative Agriculture
The Gibberellic Acid-stimulated Arabidopsis (GASA) gene family is involved in the regulation of gene expression and plant growth, development, and stress responses.
Qian Chen, Shunyuan Yong, Fan Xu, Hao Fu, Jiangbo Dang, Qiao He, Danlong Jing, Di Wu, Guolu Liang, Qigao Guo   +9 more
doaj   +1 more source

Positive Regulation of the Hrp Type III Secretion System in Pseudomonas syringae pv. phaseolicola

Molecular Plant-Microbe Interactions, 2010
Disease in compatible hosts and induction of the hypersensitive response in resistant plants by most plant-pathogenic bacteria require a functional type III secretion system (T3SS).
Inmaculada Ortiz-Martín, Richard Thwaites, Alberto P. Macho, John W. Mansfield, Carmen R. Beuzón   +4 more
doaj   +1 more source

Studies on plant gene transfer systems [PDF]

, 1989
A number of methods for the transfer of genes to plants are assessed in this work. The potential of Agrobacterium tumefaciens infection of germinating pollen tubes in vitro as a method of gene transfer was investigated and evidence presented for an ...
Sherman, Adrian
core  

Nonparametric Bayesian inference for perturbed and orthologous gene regulatory networks [PDF]

, 2012
Motivation: The generation of time series transcriptomic datasets collected under multiple experimental conditions has proven to be a powerful approach for disentangling complex biological processes, allowing for the reverse engineering of gene ...
Penfold, Christopher A., Buchanan-Wollaston, Vicky, Wild, David L., Denby, Katherine J.   +3 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source