Results 121 to 130 of about 2,494,853 (253)

A mechanism of global gene expression regulation is disrupted by multiple disease states and drug treatments. [PDF]

PLoS One
Pickard BS.
europepmc   +1 more source

Abnormal Gene Expression Regulation Mechanism of Myeloid Cell Nuclear Differentiation Antigen in Lung Adenocarcinoma. [PDF]

Biology (Basel), 2022
Tang Z, Wang L, Bajinka O, Wu G, Tan Y.
europepmc   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Sex-differentiated placental methylation and gene expression regulation has implications for neonatal traits and adult diseases. [PDF]

Nat Commun
Tekola-Ayele F, Biedrzycki RJ, Habtewold TD, Wijesiriwardhana P, Burt A, Marsit CJ, Ouidir M, Wapner R.   +7 more
europepmc   +1 more source

The Oncogenic PI3K-Induced Transcriptomic Landscape Reveals Key Functions in Splicing and Gene Expression Regulation. [PDF]

Cancer Res, 2022
Ladewig E, Michelini F, Jhaveri K, Castel P, Carmona J, Fairchild L, Zuniga AG, Arruabarrena-Aristorena A, Cocco E, Blawski R, Kittane S, Zhang Y, Sallaku M, Baldino L, Hristidis V, Chandarlapaty S, Abdel-Wahab O, Leslie C, Scaltriti M, Toska E.   +19 more
europepmc   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Gene expression regulation and polyadenylation in ulcerative colitis via long-chain RNA sequencing. [PDF]

BMC Genomics
Zhang Z, Li D, Zheng S, Zheng C, Xu H, Wang X.   +5 more
europepmc   +1 more source

Mitochondrial tRNA-Derived Fragments and Their Contribution to Gene Expression Regulation. [PDF]

Front Physiol, 2021
Shaukat AN, Kaliatsi EG, Stamatopoulou V, Stathopoulos C.   +3 more
europepmc   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Molecular Mechanisms of Gene Expression Regulation in Response to Heat Stress in <i>Hemerocallis fulva</i>. [PDF]

Plants (Basel)
Chu B, Liu W, Li J, Zhang X, Li P.
europepmc   +1 more source