Results 211 to 220 of about 2,674,080 (353)

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Sex-differentiated placental methylation and gene expression regulation has implications for neonatal traits and adult diseases. [PDF]

Nat Commun
Tekola-Ayele F, Biedrzycki RJ, Habtewold TD, Wijesiriwardhana P, Burt A, Marsit CJ, Ouidir M, Wapner R.   +7 more
europepmc   +1 more source

Investigation of reversible histone acetylation and dynamics in gene expression regulation using 3D liver spheroid model. [PDF]

Epigenetics Chromatin, 2022
Stransky S, Cutler R, Aguilan J, Nieves E, Sidoli S.   +4 more
europepmc   +1 more source

From carbohydrates to cloning: regulation of gene expression [PDF]

, 1987
Don M. Carlson
openalex   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Gene expression regulation and polyadenylation in ulcerative colitis via long-chain RNA sequencing. [PDF]

BMC Genomics
Zhang Z, Li D, Zheng S, Zheng C, Xu H, Wang X.   +5 more
europepmc   +1 more source

Abnormal Gene Expression Regulation Mechanism of Myeloid Cell Nuclear Differentiation Antigen in Lung Adenocarcinoma. [PDF]

Biology (Basel), 2022
Tang Z, Wang L, Bajinka O, Wu G, Tan Y.
europepmc   +1 more source

Regulation of renin gene expression in hypertensive rats.

, 1988
Savvas C. Makrides, R Mulinari, Vassilis I. Zannis, Haralambos Gavras   +3 more
openalex   +1 more source

Regulation of human immunodeficiency virus env expression by the rev gene product [PDF]

, 1989
Marie‐Louise Hammarskjöld, J Heimer, Björn Hammarskjöld, Indu Sangwan, Lea Albert, David Rekosh   +5 more
openalex   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source