Results 271 to 280 of about 1,893,780 (318)
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Regulation of opioid gene expression
Peptides, 1983Opioid peptides are synthesized in the form of large precursors, which contain the information for more than one biologically active peptide. Using recombinant DNA technology, three opioid precursors have been sequenced: pro-opiomelanocortin (POMC), proenkephalin and prodynorphin.
O, Civelli +6 more
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Nutritional regulation of gene expression
Theory in Biosciences, 2001The human genome has now been mapped with a complete sequence to follow shortly. The race is on to apply the vast amount of information contained in the billions of base-pairs. Concurrently, there is an increased demand from the public for perceived natural products.
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Regulation Of Neuropeptide Gene Expression
Annual Review of Neuroscience, 1990Understanding of the mechanisms of neuropeptide gene regulation has increased dramatically in the past 5 years. In large part, this increased understanding has resulted from advances in the technology of introducing reporter genes into intact cells in culture.
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Androgen regulation of gene expression
The Prostate, 1996Androgen receptors are important transcription factors regulating the expression of a number of genes in androgen-responsive cells and may play a role in prostate cancer. This article describes transcriptional suppressors and other transcription factors which may play important roles in modulating the expression of androgen receptors.
J E, Perry, M E, Grossmann, D J, Tindall
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Regulating gene expression in gene therapy
Trends in Biotechnology, 1993Ensuring that expression of introduced genes is both safe and effective necessitates directing expression to the appropriate tissue, at levels which produce a therapeutic effect. Extensive research is under way to elucidate the mechanisms and genetic elements involved in regulating expression. With the need to correlate expression levels and phenotypic
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Regulation of gene expression by light
Current Opinion in Cell Biology, 1993The past year has seen significant advances in the biochemical, genetic and molecular dissection of the light signal transduction and developmental pathways that lead to photoregulated gene expression in higher plants. A major part of recent research has focused on the assignment of biological functions to the various photoreceptors, the genetic ...
H M, Li, T, Washburn, J, Chory
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Dietary regulation of gene expression
Current Opinion in Gastroenterology, 2004The intestine has traditionally been assumed to process food by digestion and absorption. The possibility that the intestine or other genes in the body respond to diet has only slowly been appreciated.This review examines recent evidence that nutrients act on genes in the intestine and in distant sites such as the brain, liver, and skeletal muscle. The
Rachel S, Levi, I R, Sanderson
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Regulation of erythropoietin gene expression
Current Opinion in Hematology, 1995The study of erythropoietin gene expression provides a paradigm for understanding gene regulation in response to hypoxia. The sensor for detecting alterations in oxygen tension appears to be a heme protein. Ongoing transcription and protein synthesis are necessary for hypoxic induction of erythropoietin messenger RNA.
L E, Huang, H F, Bunn
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Vitamin A and regulation of gene expression
Current Opinion in Clinical Nutrition and Metabolic Care, 1998The biologically active form of vitamin A, retinoic acid, and its synthetic analogs exhibit potent anti-proliferative normalization of differentiation and anti-inflammatory activities, which appear to account for their therapeutic effects in hyperproliferative and inflammatory diseases, such as acne, psoriasis, photoaging and neoplasias.
S, Nagpal, R A, Chandraratna
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Regulation of Gene Expression by Glucocorticoids
Annual Review of Physiology, 1989Steroid hormones mediate profound physiological and developmental effects in higher eukaryotes. By interacting with their intracellular receptors in target cells, steroid hormones provide mechanisms for cellular communication and alterations in phenotypic response to environmental and internal stimuli.
K L, Burnstein, J A, Cidlowski
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