Results 291 to 300 of about 8,100,350 (339)
Some of the next articles are maybe not open access.
Regulation of histone gene expression
Current Opinion in Cell Biology, 1992Histone genes are expressed during the S phase of the cell cycle. Control is at multiple levels and is mediated by the integration of regulatory signals in response to cell-cycle progression and the onset of differentiation. Much work has been carried out on the H4 gene promoter, which appears to be organized into a series of distinct regulatory ...
Stein, Gary S. +3 more
openaire +3 more sources
Regulating gene expression in gene therapy
Trends in Biotechnology, 1993Ensuring that expression of introduced genes is both safe and effective necessitates directing expression to the appropriate tissue, at levels which produce a therapeutic effect. Extensive research is under way to elucidate the mechanisms and genetic elements involved in regulating expression. With the need to correlate expression levels and phenotypic
openaire +2 more sources
Regulation of opioid gene expression
Peptides, 1983Opioid peptides are synthesized in the form of large precursors, which contain the information for more than one biologically active peptide. Using recombinant DNA technology, three opioid precursors have been sequenced: pro-opiomelanocortin (POMC), proenkephalin and prodynorphin.
O, Civelli +6 more
openaire +2 more sources
Regulation of Neuronal Gene Expression
Naturwissenschaften, 1999Humans as multicellular organisms contain a variety of different cell types where each cell population must fulfill a distinct function in the interest of the whole organism. The molecular basis for the variations in morphology, biochemistry, molecular biology, and function of the various cell types is the cell-type specific expression of genes.
G, Thiel, M, Lietz, M, Leichter
openaire +2 more sources
Osmotic regulation of gene expression
The FASEB Journal, 1996Cells react to increased osmolality with numerous changes in gene expression. The specific genes affected differ between species, but the known osmoprotective effects of the gene products are remarkably similar, particularly with regard to cellular accumulation of compatible organic os‐ molytes. Here we concentrate on the molecular
M B, Burg, E D, Kwon, D, Kültz
openaire +2 more sources
Regulation of KiSS1 gene expression
Peptides, 2009Kisspeptins are the protein products encoded by KiSS1 gene, an important tumor metastatic suppressor and pivotal master hormone of puberty. Although KiSS1 gene is expressed in both central and peripheral tissues, the molecular mechanisms that determine the temporal and spatial expression of KiSS1 gene are not well understood.
Dali, Li, Weishi, Yu, Mingyao, Liu
openaire +2 more sources
Glucose regulation of gene expression
Current Opinion in Clinical Nutrition and Metabolic Care, 1998Regulation of gene expression by nutrients in mammals is an important mechanism allowing them to adapt to the nutritional environment. In-vivo and in-vitro experiments have demonstrated that the transcription of genes coding for lipogenic and glycolytic enzymes in liver and/or adipose tissue is upregulated by glucose.
F, Foufelle, J, Girard, P, Ferré
openaire +2 more sources
Regulation of gene expression by glucose
Current Opinion in Clinical Nutrition and Metabolic Care, 2007In addition to its metabolic function, glucose modulates gene expression which is crucial in adapting cells to variations in glycaemia. We summarize recent advances in our understanding of regulation of gene expression by glucose.In-vivo and in-vitro experiments demonstrated that glucose regulates the transcription of genes encoding not only lipogenic ...
Fouilloux-Meugnier, Emmanuelle +2 more
openaire +3 more sources
Regulation of GATA1 Gene Expression
Journal of Biochemistry, 2007GATA1 is one of the most fascinating transcription factors for biologists. It regulates many haematopoietic genes and interacts with a number of other transcription factors. Its functions are mostly conserved among vertebrates. Upon disruption of the GATA1 gene, mice show a drastic bloodless phenotype.
Makoto, Kobayashi, Masayuki, Yamamoto
openaire +2 more sources
Regulation of metallothionein gene expression
2000The rapid and robust induction of metallothioneins (MT)-I and II by a variety of inducers that include heavy toxic metals, reactive oxygen species, and different types of stress provide a useful system to study the molecular mechanisms of this unique induction process.
K, Ghoshal, S T, Jacob
openaire +2 more sources