Results 21 to 30 of about 2,701,308 (189)

TNF-alpha inhibition ameliorates HDV-induced liver damage in a mouse model of acute severe infection

open access: yesJHEP Reports, 2020
Background & Aims: HDV infection induces the most severe form of human viral hepatitis. However, the specific reasons for the severity of the disease remain unknown.
Carla Usai   +9 more
doaj   +1 more source

Administration of Insurance Rate Regulatory Laws [PDF]

open access: yes, 1950
microRNAs (miRNAs) are key posttranscriptional regulators of gene expression. In the present study, regulation of tumor-suppressor gene D-glucuronyl C5-epimerase (GLCE) by miRNA-218 was investigated. Significant downregulation of miRNA-218 expression was
Ernberg, Ingemar   +5 more
core   +3 more sources

Metabolite-dependent regulation of gene expression in trypanosoma brucei [PDF]

open access: yes, 2013
Mechanisms regulating gene expression in trypanosomatid protozoa differ significantly from those in other eukaryotes. Transcription of the genome appears to be more or less constitutive with the polyadenylation and trans-splicing of large polycistronic ...
Archer   +34 more
core   +1 more source

From obesity resistance to obesity prediction and prevention? [PDF]

open access: yes, 2016
Comment on: Regulation of hypothalamic neuropeptides gene expression in diet induced obesity resistant rats: possible targets for obesity prediction?
Cassano, Tommaso, Gaetani, Silvana
core   +4 more sources

3′UTR of mRNA Encoding CPEB Protein Orb2 Plays an Essential Role in Intracellular Transport in Neurons

open access: yesCells, 2023
Intracellular trafficking plays a critical role in the functioning of highly polarized cells, such as neurons. Transport of mRNAs, proteins, and other molecules to synaptic terminals maintains contact between neurons and ensures the transmission of nerve
Eugene N. Kozlov   +9 more
doaj   +1 more source

Four-way regulation of mosquito yolk protein precursor genes by juvenile hormone-, ecdysone-, nutrient-, and insulin-like peptide signaling pathways. [PDF]

open access: yes, 2014
Anautogenous mosquito females require a meal of vertebrate blood in order to initiate the production of yolk protein precursors by the fat body. Yolk protein precursor gene expression is tightly repressed in a state-of-arrest before blood meal-related ...
Attardo, Geoffrey M   +3 more
core   +2 more sources

miRNA-Mediated KHSRP Silencing Rewires Distinct Post-transcriptional Programs during TGF-β-Induced Epithelial-to-Mesenchymal Transition

open access: yesCell Reports, 2016
Epithelial-to-mesenchymal transition (EMT) confers several traits to cancer cells that are required for malignant progression. Here, we report that miR-27b-3p-mediated silencing of the single-strand RNA binding protein KHSRP is required for transforming ...
Margherita Puppo   +8 more
doaj   +1 more source

Comparative genetic, proteomic and phosphoproteomic analysis of C. elegans embryos with a focus on ham-1/STOX and pig-1/MELK in dopaminergic neuron development

open access: yesScientific Reports, 2017
Asymmetric cell divisions are required for cellular diversity and defects can lead to altered daughter cell fates and numbers. In a genetic screen for C.
Sarah-Lena Offenburger   +4 more
doaj   +1 more source

Functional Characteristics of Gene Expression Motifs with Single and Dual Strategies of Regulation

open access: yes, 2016
Transcriptional regulation by transcription factors and post-transcriptional regulation by microRNAs constitute two major modes of regulation of gene expression.
Bose, Indrani   +2 more
core   +1 more source

miRNAs as Regulators of Antidiabetic Effects of Fucoidans [PDF]

open access: yes, 2019
open access articleDiabetes mellitus is a metabolic disease with a high mortality rate worldwide. MicroRNAs (miRNAs), and other small noncoding RNAs, serve as endogenous gene regulators through binding to specific sequences in RNA and modifying gene ...
Arroo, R. R. J.   +8 more
core   +1 more source

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