Results 291 to 300 of about 1,661,421 (342)
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2012
Gene expression can be regulated at the stage of transcription, RNA processing (post- transcriptional changes), and translation. In prokaryotes, the on–off of transcription serves as the main regulatory control of the gene expression whereas, in eukaryotes, more complex regulatory mechanism of transcription takes place.
Sarika Garg, Anil Kumar, Neha Garg
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Gene expression can be regulated at the stage of transcription, RNA processing (post- transcriptional changes), and translation. In prokaryotes, the on–off of transcription serves as the main regulatory control of the gene expression whereas, in eukaryotes, more complex regulatory mechanism of transcription takes place.
Sarika Garg, Anil Kumar, Neha Garg
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British Medical Bulletin, 1991
A fundamental tenet of biology is that the phenotype of an organism is ultimately determined by its complement of genes. In multicellular organisms, it is the regulated pattern of expression of genes which determines the proliferation and differentiation of individual cell lineages and hence establishes the adult phenotype.
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A fundamental tenet of biology is that the phenotype of an organism is ultimately determined by its complement of genes. In multicellular organisms, it is the regulated pattern of expression of genes which determines the proliferation and differentiation of individual cell lineages and hence establishes the adult phenotype.
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New England Journal of Medicine, 1994
Genetics is a language with rules of composition that give the tissues of the body their special traits. These rules govern the activation of particular subgroups of genes, which determine not only the unique characteristics of a cell type but also whether it remains quiescent, divides, or dies. The timing of gene activation is very important. If genes
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Genetics is a language with rules of composition that give the tissues of the body their special traits. These rules govern the activation of particular subgroups of genes, which determine not only the unique characteristics of a cell type but also whether it remains quiescent, divides, or dies. The timing of gene activation is very important. If genes
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2011
Although all cells in a multicellular organism carry the same genes, they become specialized cells with different functions, regulated by the unique expression of the genes they carry. This chapter introduces the subject of prokaryotic and eukaryotic regulation of gene expression. Prokaryotes principally turn their genes on and off using activators and
Chung-Eun Ha, Nadhipuram V. Bhagavan
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Although all cells in a multicellular organism carry the same genes, they become specialized cells with different functions, regulated by the unique expression of the genes they carry. This chapter introduces the subject of prokaryotic and eukaryotic regulation of gene expression. Prokaryotes principally turn their genes on and off using activators and
Chung-Eun Ha, Nadhipuram V. Bhagavan
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Expression and regulation of the SOST gene
Hereditas (Beijing), 2013Sclerostin(SOST), mainly expressed in osteocytes, is a negative regulator of bone formation. Hormones PTH and E2 inhibit the expression of the SOST gene. Transcription factors Osterix, Runx2, and Mef2c promote the SOST expression, while Sirt1 negatively regulates the SOST expression.
Da-Xia Ding +3 more
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Gene Regulation and Expression
1992A gene is a segment of DNA consisting of codons specifying the amino acids for a protein and of control sequences which regulate gene expression. When a cell divides, the entire human genome, that is, all the DNA stored within the nucleus, must be copied. In Figure 2.1 the replication of DNA is demonstrated.
Dennis W. Ross, Dennis W. Ross
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Androgen regulation of gene expression
The Prostate, 1996Androgen receptors are important transcription factors regulating the expression of a number of genes in androgen-responsive cells and may play a role in prostate cancer. This article describes transcriptional suppressors and other transcription factors which may play important roles in modulating the expression of androgen receptors.
Donald J. Tindall +2 more
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Regulation of Cytokine Gene Expression
Annual Review of Immunology, 1988Following the isolation and characterization of many cytokine genes, we began to understand the mechanisms regulating cytokine gene expression. Needless to say, understanding the mechanisms by which induction of gene expression occurs in a transient, cell type-specific manner in response to extracellular inducers is a central issue in eukaryotic ...
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Regulated Gene Expression in Gene Therapy
Annals of the New York Academy of Sciences, 2001Abstract: The original model of gene therapy, that of efficient delivery, durable transfer, and stable expression of transgenes to correct a gene defect underlying an inherited disease, is limited in light of improved understanding of the processes involved.
James M. Wilson +2 more
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Regulation Of Neuropeptide Gene Expression
Annual Review of Neuroscience, 1990Understanding of the mechanisms of neuropeptide gene regulation has increased dramatically in the past 5 years. In large part, this increased understanding has resulted from advances in the technology of introducing reporter genes into intact cells in culture.
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