Results 81 to 90 of about 12,462,452 (401)

Lineage-Specific Expansion of IFIT Gene Family: An Insight into Coevolution with IFN Gene Family

open access: yesPLoS ONE, 2013
In mammals, IFIT (Interferon [IFN]-induced proteins with Tetratricopeptide Repeat [TPR] motifs) family genes are involved in many cellular and viral processes, which are tightly related to mammalian IFN response.
Y. Liu   +3 more
semanticscholar   +1 more source

The Evolution of Mammalian Gene Families

open access: yesPLoS ONE, 2006
Gene families are groups of homologous genes that are likely to have highly similar functions. Differences in family size due to lineage-specific gene duplication and gene loss may provide clues to the evolutionary forces that have shaped mammalian genomes. Here we analyze the gene families contained within the whole genomes of human, chimpanzee, mouse,
Demuth, Jeffery P   +4 more
openaire   +7 more sources

Identification of a Carcinoembryonic Antigen Gene Family in the Rat [PDF]

open access: yes, 1989
The existence of a carcinoembryonic antigen (CEA)-like gene family in rat has been demonstrated through isolation and sequencing of the N- terminal domain exons of presumably five discrete genes (rnCGM1-5).
Barnert, Sabine   +5 more
core  

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

Evolutionary Developments in Plant Specialized Metabolism, Exemplified by Two Transferase Families

open access: yesFrontiers in Plant Science, 2019
Plant specialized metabolism emerged from the land colonization by ancient plants, becoming diversified along with plant evolution. To date, more than 1 million metabolites have been predicted to exist in the plant kingdom, and their metabolic processes ...
Hiroaki Kusano   +5 more
doaj   +1 more source

Genome-Wide Identification and Expression Analysis of SNARE Genes in Brassica napus

open access: yesPlants, 2022
SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) are central components that drive membrane fusion events during exocytosis and endocytosis and play important roles in different biological processes of plants. In this study,
Jing Xu   +9 more
doaj   +1 more source

The human crystallin gene families [PDF]

open access: yesHuman Genomics, 2012
Crystallins are the abundant, long-lived proteins of the eye lens. The major human crystallins belong to two different superfamilies: the small heat-shock proteins (α-crystallins) and the βγ-crystallins. During evolution, other proteins have sometimes been recruited as crystallins to modify the properties of the lens.
openaire   +4 more sources

Characterization and gene expression analysis of the cir multi-gene family of plasmodium chabaudi chabaudi (AS) [PDF]

open access: yes, 2012
Background: The pir genes comprise the largest multi-gene family in Plasmodium, with members found in P. vivax, P. knowlesi and the rodent malaria species.
Berriman, Matthew   +11 more
core   +3 more sources

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Genome-wide identification and expression analysis of calcium-dependent protein kinase in tomato

open access: yesFrontiers in Plant Science, 2016
Calcium-dependent protein kinases (CDPKs) play critical roles in regulating growth, development and stress response in plants. Information about CDPKs in tomato, however, remains obscure although it is one of the most important model crops in the world ...
Zhangjian eHu   +8 more
doaj   +1 more source

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