Results 91 to 100 of about 1,855,658 (333)

Dual gene activation and knockout screen reveals directional dependencies in genetic networks. [PDF]

open access: yes, 2018
Understanding the direction of information flow is essential for characterizing how genetic networks affect phenotypes. However, methods to find genetic interactions largely fail to reveal directional dependencies. We combine two orthogonal Cas9 proteins
Biton, Anne   +12 more
core   +2 more sources

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Hybridization rate and hybrid fitness for Camelina microcarpa Andrz. ex DC (♀) and Camelina sativa (L.) Crantz(Brassicaceae) (♂)

open access: yesEvolutionary Applications, 2019
Hybridization between crops and their wild relatives has the potential to introduce novel variation into wild populations. Camelina (Camelina sativa) is a promising oilseed and cultivars with modified seed characteristics and herbicide resistance are in ...
Sara L. Martin   +5 more
doaj   +1 more source

Systematic considerations on two species of nectarivorous bats (Anoura caudifer and A. geoffroyi) based on barcoding sequences

open access: yesActa Biológica Colombiana, 2020
As a product of recent revisions of the nectivore bat genus Anoura (Glossophaginae: Anourina), new species have been described, and several taxa have been elevated to the specific level in the so-called Anoura caudifer and A.
Andrés Felipe Vargas Arboleda   +2 more
doaj   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

Landscape genomics to the rescue of a tropical bee threatened by habitat loss and climate change

open access: yesEvolutionary Applications, 2019
Habitat degradation and climate change are currently threatening wild pollinators, compromising their ability to provide pollination services to wild and cultivated plants.
Rodolfo Jaffé   +20 more
doaj   +1 more source

Inter-population differences in otolith morphology are genetically encoded in the killifish Aphanius fasciatus (Cyprinodontiformes)

open access: yesScientia Marina, 2013
Inter-population differences in otolith shape, morphology and chemistry have been used effectively as indicators for stock assessment or for recognizing environmental adaptation in fishes.
Ali Annabi   +2 more
doaj   +1 more source

Surprisingly Little Population Genetic Structure In A Fungus-Associated Beetle Despite Its Exploitation Of Multiple Hosts [PDF]

open access: yes, 2013
In heterogeneous environments, landscape features directly affect the structure of genetic variation among populations by functioning as barriers to gene flow.
Brodie, E. D., III   +3 more
core   +2 more sources

Population structure and speciation in the dragonfly Sympetrum striolatum/nigrescens (Odonata: Libellulidae): An analysis using AFLP markers

open access: yesEuropean Journal of Entomology, 2009
There has been a long-standing debate as to whether Sympetrum striolatum (Charpentier, 1840) and the darker northern form, S. nigrescens (Lucas, 1912) should be recognised as separate species of dragonfly.
Katharine A. PARKES   +4 more
doaj   +1 more source

Isolation mediates persistent founder effects on zooplankton colonisation in new temporary ponds [PDF]

open access: yes, 2017
Understanding the colonisation process in zooplankton is crucial for successful restoration of aquatic ecosystems. Here, we analyzed the clonal and genetic structure of the cyclical parthenogenetic rotifer Brachionus plicatilis by following populations ...
Badosa, Anna   +4 more
core   +2 more sources

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