Results 111 to 120 of about 1,973,564 (301)
Scientia Marina, 2013 Inter-population differences in otolith shape, morphology and chemistry have been used effectively as indicators for stock assessment or for recognizing environmental adaptation in fishes.
Ali Annabi +2 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
European Journal of Entomology, 2009 There has been a long-standing debate as to whether Sympetrum striolatum (Charpentier, 1840) and the darker northern form, S. nigrescens (Lucas, 1912) should be recognised as separate species of dragonfly.
Katharine A. PARKES +4 more
doaj +1 more source
Science, 2012 Ecology![Figure][1] CREDIT: © PETE MCBRIDE/NATIONAL GEOGRAPHIC SOCIETY/CORBIS Antibiotic resistance is becoming an urgent problem. We point one finger at lax medication sales, and another at livestock husbandry, but there is also an ancient background signal of antibiotic resistance, in part stemming from the natural functions of these molecules in ...
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Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Nature, 1993 Species Evolution: The Role of Chromosome Change. By Max King. Cambridge University Press: 1993. Pp. 336. £40, $59.95.
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Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Aquatic Insects in Eastern Australia: A Window on Ecology and Evolution of Dispersal in Streams
Insects, 2011 Studies of connectivity of natural populations are often conducted at different timescales. Studies that focus on contemporary timescales ask questions about dispersal abilities and dispersal behavior of their study species.
Alison J. McLean +3 more
doaj +1 more source
, 2014 Patterns of isolation-by-distance arise when population differentiation increases with increasing geographic distances. Patterns of isolation-by-distance are usually caused by local spatial dispersal, which explains why differences of allele frequencies ...
Blum, Michael G. B. +1 more
core +3 more sources
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source