Results 121 to 130 of about 1,946,714 (353)
Rare Alleles as Indicators of Gene Flow [PDF]
A. method for estimating the average level of gene flow in a subdivided population, as measured by the average number of migrants exchanged between local populations, Nm, is presented. The results from a computer simulation model show that the logarithm of Nm is approximately linearly related to the logarithm of the average frequency of private alleles,
openaire +2 more sources
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang+2 more
wiley +1 more source
Hybrid zone dynamics under weak Haldane's rule [PDF]
The ability of genetic isolation to block gene flow plays a key role in the speciation of sexually reproducing organisms. This paper analyses the hybrid zone dynamics affected by "weak" Haldane's rule, namely the incomplete hybrids inferiority (sterility/inviability) against the heterogametic (XY or ZW) sex caused by a Dobzhansky-Muller incompatibility.
arxiv
Brucella NyxA and NyxB dimerization enhances effector function during infection
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre+4 more
wiley +1 more source
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg+2 more
wiley +1 more source
Genetic variability of Chilean and Peruvian surfclams (Donax marincovichi and Donax obesulus) [PDF]
Exposed intertidal sandy beaches are commonly dominated by surf clams of the genus Donax. In Peru and Chile these bivalves play an important role for artisanal fisheries.
Arntz, Wolf+6 more
core
Gene flow across geographical barriers - scaling limits of random walks with obstacles
In this paper, we study the scaling limit of a class of random walks which behave like simple random walks outside of a bounded region around the origin and which are subject to a partial reflection near the origin.
Forien, Raphael
core +2 more sources
Butterfly gene flow goes berserk [PDF]
A new study shows that genomic introgression between two Heliconius butterfly species is not solely confined to color pattern loci.
openaire +4 more sources
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro+2 more
wiley +1 more source
Optimizing information flow in small genetic networks. IV. Spatial coupling [PDF]
We typically think of cells as responding to external signals independently by regulating their gene expression levels, yet they often locally exchange information and coordinate. Can such spatial coupling be of benefit for conveying signals subject to gene regulatory noise?
arxiv