Gene flow and differential mortality in a contact zone between two Albinaria species (Gastropoda; Clausiliidae) [PDF]
Sinos Giokas+2 more
openalex +1 more source
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides+13 more
wiley +1 more source
Pangenome analysis reveals yield- and fiber-related diversity and interspecific gene flow in Gossypium barbadense L. [PDF]
Meng Q+21 more
europepmc +1 more source
On the relation between gene flow theory and genetic gain [PDF]
Piter Bijma, John Woolliams
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β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero+8 more
wiley +1 more source
Additional Complexity in Historic and Contemporary Gene Flow Among Hoary, Vancouver Island, and Olympic Marmots Revealed by Microsatellites and Ultraconserved Elements. [PDF]
Hamilton NM+4 more
europepmc +1 more source
BARRIERS TO GENE FLOW INEMBIOTOCA JACKSONI, A MARINE FISH LACKING A PELAGIC LARVAL STAGE [PDF]
Giacomo Bernardi
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Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li+12 more
wiley +1 more source
Constraints to gene flow increase the risk of genome erosion in the Ngorongoro Crater lion population. [PDF]
Dussex N+7 more
europepmc +1 more source
Autosomal, mtDNA, and Y-Chromosome Diversity in Amerinds: Pre- and Post-Columbian Patterns of Gene Flow in South America [PDF]
Natalia Mesa+12 more
openalex +1 more source