Results 221 to 230 of about 1,946,714 (353)

Pervasive gene flow despite strong and varied reproductive barriers in swordtails. [PDF]

Nat Ecol Evol
Aguillon SM, Haase Cox SK, Langdon QK, Gunn TR, Baczenas JJ, Banerjee SM, Donny AE, Moran BM, Fascinetto-Zago P, Gutiérrez-Rodríguez C, Ríos-Cárdenas O, Morris MR, Powell DL, Schumer M.   +13 more
europepmc   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

Intersectional gene flow between insular endemics ofIlex(Aquifoliaceae) on the Bonin Islands and the Ryukyu Islands [PDF]

, 2000
Hiroaki Setoguchi, Itta Watanabe
openalex   +1 more source

Pangenome analysis reveals yield- and fiber-related diversity and interspecific gene flow in Gossypium barbadense L. [PDF]

Nat Commun
Meng Q, Xie P, Xu Z, Tang J, Hui L, Gu J, Gu X, Jiang S, Rong Y, Zhang J, Udall JA, Grover CE, Zheng K, Chen Q, Kong J, Wang M, Nie X, Lin Z, Jin S, Wendel JF, Zhang X, Yuan D.   +21 more
europepmc   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

Extensive gene flow within sibling species in the deep-sea fish Beryx splendens [PDF]

, 2000
Galice Hoarau, Philippe Borsa
openalex   +1 more source

Constraints to gene flow increase the risk of genome erosion in the Ngorongoro Crater lion population. [PDF]

Commun Biol
Dussex N, Jansson I, van der Valk T, Packer C, Norman A, Kissui BM, E Mjingo E, Spong G.   +7 more
europepmc   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

Adenovirus-Mediated Human Tissue Kallikrein Gene Delivery Inhibits Neointima Formation Induced by Interruption of Blood Flow in Mice [PDF]

, 2000
Costanza Emanueli, Maria Bonaria Salis, Julie Chao, Lee Chao, Jun Agata, Kuei-Fu Lin, Antonella Munaò, Stefania Straino, Alessandra Minasi, Maurizio C. Capogrossi, Paolo Madeddu   +10 more
openalex   +1 more source

Selection Over Small and Large Spatial Scales in the Face of High Gene Flow. [PDF]

Mol Ecol
Rumberger C, Armstrong M, Kim M, Ponce R, Melendez J, DeBiasse M, Caplins S, Bay R.   +7 more
europepmc   +1 more source