Results 161 to 170 of about 11,790,132 (329)

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Molecular inflammatory expression profiles associated with the frequency of pain in individuals with sickle cell disease. [PDF]

Blood Adv
Mucalo Katunaric L, Jia S, Singh A, Roethle MF, Panepinto JA, Brousseau DC, Hessner MJ, Brandow AM.   +7 more
europepmc   +1 more source

The Gene Frequency of Acute Werdnig-Hoffmann Disease (SMA Type 1). A Total Population Survey in North-East England

Journal of Medical Genetics, 1973
J. Pearn
semanticscholar   +1 more source

FERTILITY GENES IN NATURAL POPULATIONS OF DROSOPHILA MELANOGASTER. I. FREQUENCY, ALLELISM AND PERSISTENCE OF STERILITY GENES [PDF]

, 1973
Chozo Oshima, Takao Watanabe
openalex   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

Dopamine D2 receptor gene Taq 1A polymorphism: genetic architecture in Indian population and comparison to global populations. [PDF]

Front Genet
Chaudhary A, Kumar P, Sharma B, Rai V.
europepmc   +1 more source

MEASUREMENT OF GENE FREQUENCY DRIFT IN SMALL POPULATIONS

, 1955
J. Crow, N. Morton
semanticscholar   +1 more source

A MUTANT GENE MAINTAINED AT HIGH FREQUENCY IN SPITE OF COMPLETE SELECTION AGAINST THE HOMOZYGOTE

, 1968
Peter S. Dawson
openalex   +2 more sources

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Detection of the distribution frequency of Diego blood type based on multiplex droplet digital PCR. [PDF]

Sci Rep
Chu X, Wang J, Wu D, Mao J, Zhang Z, Xu H, Ma C.   +6 more
europepmc   +1 more source