Results 241 to 250 of about 13,199,223 (392)

Analysis of chromatin structure reveals the connection between sQTLs and the splicing of distant genes. [PDF]

Sci Rep
Eralp B, Sefer E.
europepmc   +1 more source

P105. Evaluating the frequency of MEFV gene mutation and its impact on the clinical course in patient with inflammatory bowel disease [PDF]

, 2015

openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Multi-Omics Analysis of the Co-Expression Features of Specific Neighboring Gene Pairs Suggests an Association with Catechin Regulation in <i>Camellia sinensis</i>. [PDF]

Genes (Basel)
Lian S, Ren F, Cai S, Wang Z, Tu Y, Gong K, Zhang W.   +6 more
europepmc   +1 more source

Estimation of prokaryotic supergenome size and composition from gene frequency distributions. [PDF]

BMC Genomics, 2014
Lobkovsky AE, Wolf YI, Koonin EV.
europepmc   +1 more source

Frequency of three common card15/Nod 2 gene mutations and genotype/ phenotype correlation in a single center german IBD cohort

, 2003
Fabian Schnitzler, Peter Lohse, Michael Sackmann, Burkhard Goeke, Thomas Ochsenkühn   +4 more
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Mitochondrial Transporter ABCB10 Protects Against Doxorubicin-Induced Respiratory Muscle Dysfunction Independent of Changes to Diaphragm Accumulation. [PDF]

J Cachexia Sarcopenia Muscle
Smuder AJ, Doerr V, Jacintho Moritz CE, Li J, Nguyen BL.   +4 more
europepmc   +1 more source

Frequency of G2677T/A and C3435T polymorphisms of MDR1 gene in preeclamptic women

, 2013
Anna Bogacz, P.M. Mrozikiewicz, Joanna Bartkowiak-Wieczorek, Aleksandra Kowalska, Donata Deka-Pawlik, Edmund Grześkowiak, Agnieszka Seremak‐Mrozikiewicz, Magdalena Barlik, Krzysztof Drews   +8 more
openalex   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source