Results 251 to 260 of about 3,986,989 (305)

Myeloid/lymphoid neoplasms with eosinophilia and tyrosine kinase gene fusion: report of two cases with different clinical presentation. [PDF]

Pathologica
Merenda E, Paciaroni K, Scalzulli E, Breccia M, Licci S, Bizzoni L, Giordano C, Rullo E.   +7 more
europepmc   +1 more source

Unveiling Unique EWS: CREB1 Gene Fusion in a Jejunal Tumor. [PDF]

Indian J Surg Oncol
Chhabra R, Dodagoudar C, Narwariya A, Mane P, Osama MA.   +4 more
europepmc   +1 more source

Development of Peptidomimetic Inhibitors of the ERG Gene Fusion Product in Prostate Cancer. [PDF]

Cancer Cell
Wang X, Qiao Y, Asangani IA, Ateeq B, Poliakov A, Cieślik M, Pitchiaya S, Chakravarthi BVSK, Cao X, Jing X, Wang CX, Apel IJ, Wang R, Ching-Yi Tien J, Juckette KM, Yan W, Jiang H, Wang S, Varambally S, Chinnaiyan AM.   +19 more
europepmc   +1 more source

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Targeting gene fusions in glioma

Current Opinion in Neurology, 2021
Purpose of review Glioma represents of variety of brain malignancies, the majority of which confer a poor prognosis despite treatment. With the widespread use of next-generation sequencing, gene fusions are being found in greater numbers.
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Gene therapy for spinal fusion

The Spine Journal, 2005
Spinal fusion will continue to be an important part of the surgical treatment of spinal pathology for the foreseeable future. Traditional challenges to successful spinal fusion surgery include autograft donor site morbidity and pseudoarthrosis. Recent advances in the understanding of the biology of bone formation have allowed the development of ...
Frank M, Phillips, Patrick M, Bolt, Tong-Chuan, He, Rex C, Haydon   +3 more
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Fusion genes in epithelial neoplasia

Journal of Clinical Pathology, 2009
Recurrent chromosomal rearrangements with the formation of fusion genes have been traditionally associated with haematological and mesenchymal neoplasms. This view has cultivated the erroneous impression that the oncogenic mechanisms present in these tumours are fundamentally different from those found in epithelial neoplasms. In spite of the fact that,
H, Zhang, A M, Oliveira
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Irradiation and fusion gene transfer

Molecular Biotechnology, 1995
Irradiation and fusion gene transfer (IFGT) is a technique that spans the gap between the limitations of molecular methods and somatic-cell genetics, allowing the separation of DNA fragments between 0.25 and 30 Mb in size. In conjunction with genetic linkage analysis and physical mapping techniques, IFGT provides a very useful addition to methods for ...
M A, Walter, P N, Goodfellow
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Gene Fusion Discovery with INTEGRATE

2019
Next-generation sequencing (NGS) has become the primary technology for discovering gene fusions. Decreasing NGS costs have resulted in a growing quantity of patients with whole transcriptome sequencing (RNA-seq) and whole genome sequencing (WGS) data.
Jin, Zhang, Christopher A, Maher
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Fusion genes and transcripts in neoplasia

Molecular Biology, 2011
Chromosomal rearrangements resulting in the formation of fusion genes are common events in carcinogenesis. There are more than 440 known fusion genes found in both malignant and benign tumors. The mechanism of transcription induced chimerism (TIC) contributes to fusion transcripts in normal human tissues.
T V, Kekeeva, L É, Zavalishina, G A, Frank, D V, Zaletaev   +3 more
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