Results 11 to 20 of about 405,164 (304)
BioTechniques, 2006 A number of natural microRNA (miRNA) hairpins have been found in clusters of multiple identical or different copies, suggesting that effects of miRNAs can be enhanced and multiple genes can be regulated together by encoding multiple miRNA hairpins in a ...
Daqian Sun +4 more
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Ribonucleic acid interference induced gene knockdown
Journal of Indian Society of Periodontology, 2013 Despite major advances in periodontal regeneration over the past three decades, complete regeneration of the lost periodontium on a regular and predictable basis in humans has still remained elusive.
Sruthima N. V. S. Gottumukkala +2 more
doaj +3 more sources
HAND1 knockdown disrupts trophoblast global gene expression
Physiological Reports, 2023 Congenital heart disease (CHD) affects nearly 1% of births annually, and CHD pregnancies carry increased risk of developing pathologies of abnormal placentation.
Robert Fresch +4 more
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RdsA Is a Global Regulator That Controls Cell Shape and Division in Rhizobium etli
Frontiers in Microbiology, 2022 Unlike other bacteria, cell growth in rhizobiales is unipolar and asymmetric. The regulation of cell division, and its coordination with metabolic processes is an active field of research.
Sofía Martínez-Absalón +3 more
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IL-6/IFN-γ double knockdown CAR-T cells reduce the release of multiple cytokines from PBMCs in vitro
Human Vaccines & Immunotherapeutics, 2022 CD19-targeted chimeric antigen receptor T (anti-CD19 CAR-T) cells have shown good therapeutic results in the treatment of CD19 + B cell acute lymphocytic leukemia and lymphoma.
Huihui Zhang +3 more
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RNAi and CRISPR/Cas9 as Functional Genomics Tools in the Neotropical Stink Bug, Euschistus heros
Insects, 2020 The Neotropical brown stink bug, Euschistus heros, is one of the most important stink bug pests in leguminous plants in South America. RNAi and CRISPR/Cas9 are important and useful tools in functional genomics, as well as in the future development of new
Deise Cagliari +3 more
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Experimental Models for the Study of Hereditary Cornification Defects
Biomedicines, 2021 Ichthyoses comprise a broad spectrum of keratinization disorders due to hereditary defects of cornification. Until now, mutations in more than 50 genes, mostly coding for structural proteins involved in epidermal barrier formation, have been identified ...
Dragan Copic +5 more
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The prospects for the use of drugs based on the phenomenon of RNA interference against HIV infection
Вопросы вирусологии, 2022 The human immunodeficiency virus (HIV) is currently one of the most pressing global health problems. Since its discovery in 1978, HIV has claimed the lives of more than 35 million people, and the number of people infected today reaches 37 million. In the
Evgenij A. Pashkov +7 more
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Heritable and stable gene knockdown in rats [PDF]
Proceedings of the National Academy of Sciences, 2006 The rat has served as an excellent model for studies on animal physiology and as a model for human diseases such as diabetes and alcoholism; however, genetic studies have been limited because of the inability to knock out genes.
Christina Tenenhaus, Dann +3 more
openaire +2 more sources
Вопросы вирусологии, 2021 COVID-19 has killed more than 4 million people to date and is the most significant global health problem. The first recorded case of COVID-19 had been noted in Wuhan, China in December 2019, and already on March 11, 2020, World Health Organization ...
E. A. Pashkov +6 more
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