Results 201 to 210 of about 405,164 (304)

Programmable Gene Knockdown in Diverse Bacteria Using Mobile-CRISPRi. [PDF]

Curr Protoc Microbiol, 2020
Banta AB, Ward RD, Tran JS, Bacon EE, Peters JM.   +4 more
europepmc   +1 more source

Annexin A13 Protects Against Acute Kidney Injury by Inactivating TGF‐β/Smad3 Signaling

Advanced Science, EarlyView.
ANXA13 is negatively regulated by Smad3 and exerts its protective role in AKI by inactivating TGF‐β/Smad3 signaling and Smad3‐p21 cell cycle arrest pathway through binding to TβRI, inhibiting the interaction between TβRI and TβRII, thereby suppressing TβRI phosporylation.
Jiaxiao Li, Chen Wu, Yuqi Zhu, Zicheng Liu, Wenjuan Yu, Andrew Lukwaro, Yu Zhong, Guoqiang Xie, Lili Zhou, Xiaoru Huang, Hui‐yao Lan, Junzhe Chen, Ying Tang   +12 more
wiley   +1 more source

CCDC41 Drives Oocyte Meiotic Progression by Promoting Rab11a/Rab7‐Positive Vesicle Fusion with Target Membranes

Advanced Science, EarlyView.
CCDC41 is essential for meiotic maturation in mouse oocytes through regulating Rab7‐positive endosomes fusion with lysosomes and Rab11a‐positive vesicle fusion with the plasma membrane. Abstract Coiled‐coil domain‐containing protein 41 (CCDC41), a core component of centriolar distal appendages involved in centriole assembly and ciliary vesicle docking,
Ying Tian, Jiatong Li, Jingyi Kang, Xiangning Xu, Bicheng Wang, Shuo Lou, Jingyu Li, Yuying Yang, Yanbing Zhang, Yangzi Zheng, Jing Weng, Yuanjing Liang, Wei Ma   +12 more
wiley   +1 more source

Protocol for gene knockdown using siRNA in primary cultured neonatal murine microglia. [PDF]

STAR Protoc
Kato Y, Takatori S, Akahori A, Etani H, Chu YN, Tomita T.   +5 more
europepmc   +1 more source

Knockdown of lncRNA BDNF-AS suppresses neuronal cell apoptosis via downregulating miR-130b-5p target gene PRDM5 in acute spinal cord injury

, 2018
Huafeng Zhang, Danzhen Li, Yi Zhang, Jianqiang Li, Sheng-li Ma, Jianwei Zhang, Yuanyuan Xiong, Wengang Wang, Ning Li, Lei Xia   +9 more
openalex   +1 more source

Bisphenol B Exposure Induces Miscarriage by Suppressing Migration/Invasion and Migrasome Formation

Advanced Science, EarlyView.
BPB (Bisphenol B) exposure up‐regulates ER (estrogen receptor) levels, enhances its interactions with the lnc‐HZ04 promoter region, and thus promotes ER‐mediated lnc‐HZ04 transcription. Subsequently, lnc‐HZ04 suppresses TCF4 (transcription factor 4)‐mediated PKCA (protein kinase C alpha) transcription and subsequently suppresses migration/invasion and ...
Wenxin Huang, Manli Wang, Yi Sun, Xiaoping Yue, Xun Li, Yanbing Lin, Geng Guo, Depeng Zhao, Qigang Fan, Xiaoling Ma, Zhihong Zhang, Shuaishuai Xing, Xiaoting Shen, Huidong Zhang   +13 more
wiley   +1 more source

Protocol for gene knockdown using siRNA in organotypic cultures of murine gastric muscle. [PDF]

J Smooth Muscle Res
Taheri N, Choi EL, Zhang Y, Hayashi Y.
europepmc   +1 more source

Effect of siRNA-mediated knockdown of eIF3c gene on survival of colon cancer cells [PDF]

, 2013
Ning Song, Yan Wang, Xiaodong Gu, Zongyou Chen, Liubin Shi   +4 more
openalex   +1 more source

Tissue‐Resident Macrophage‐Derived E3 Ligase SMURF2 Restricts Autoimmune Inflammation by Mediating the Degradation of p‐TBK1

Advanced Science, EarlyView.
Dysregulated Tissue resident macrophage (TRMs) link to autoimmune inflammation. SMURF2 mediates Lys‐27 (K27)‐linked ubiquitination of p‐TBK1 and its degradation, which inhibits CSF1R signaling‐triggered TRM proliferation, thereby restraining the autoimmune inflammation.
Xiang An, Jun Li, Lingling Wang, Chengyuan Li, Zhenpeng Jin, Yushi Yao, Minmin Jiang, Wenlong Lin, Xiaojian Wang   +8 more
wiley   +1 more source

Gene-knockdown Methods for Silencing Nuclear-localized Insulin Receptors in Lung Adenocarcinoma Cells: A Bioinformatics Approach. [PDF]

Curr Genomics
Ren Q, Ma H, Wang L, Qin J, Tian M, Zhang W.   +5 more
europepmc   +1 more source