Results 241 to 250 of about 139,185 (274)

Identification of <i>STMN1</i> as a lactylation‑related driver of lung cancer progression using Mendelian randomization. [PDF]

Mol Med Rep
Cai Y, Zhong Y, Wang H, Zhu S, Huang F, Zhang Q, Hu S.   +6 more
europepmc   +1 more source

HSV ICP27 hijacks host splicing factor SRSF3 to regulate pre-mRNA splicing and export for viral gene expression and immune evasion. [PDF]

PLoS Pathog
Tang S, Patel A, Takeda K, Peden K, Krause PR.   +4 more
europepmc   +1 more source

Functional roles of NR4A transcription factors in GnRH regulation of gonadotropin gene expression and secretion in rat primary pituitary cells. [PDF]

J Reprod Dev
Terashima R, Tomiyama Y, Kurusu S, Kawaminami M.   +3 more
europepmc   +1 more source

RNAi-mediated knockdown of the poultry red mite cathepsin D-1 impacts haemoglobin digestion. [PDF]

Parasit Vectors
Chen W, Defty NR, Bartley K, Nunn F, Schiavone A, Bowman AS, Hayward AD, Burgess STG, Nisbet AJ, Price DRG.   +9 more
europepmc   +1 more source

The role of SPP1 in evaluating the prognosis, immune infiltration, and drug sensitivity of hepatocellular carcinoma. [PDF]

PLoS One
Cui K, Li X, Li Y, Li Z, Wang D, Wang X, Qin S, Li J, Long J.   +8 more
europepmc   +1 more source

Limonin induces ferroptosis in cervical squamous cell carcinoma by activating the expression of soluble epoxide hydrolase 2 protein. [PDF]

PLoS One
Wu Q, Bai S, Wang P, Han L, Song L, Su L, Ren Y.   +6 more
europepmc   +1 more source

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Knockdown of survivin gene by vector-based short hairpin RNA technique induces apoptosis and growth inhibition in Burkitt's lymphoma Raji cell line.

Neoplasma, 2006
Survivin is the smallest member of mammalian IAP (inhibitor of apoptosis) family. It is ubiquitous during embryonic development but is not expressed in normal post-natal tissues, except the thymus, colonic epithelial cells and CD34+ hematopoietic stem cells. However, its expression is upregulated during neoplastic transformation in both solid organ and
Cong-Min, Gu, You-Kai, Zhu, Yi-Hui, Ma, Meng, Zhang, Bing, Liao, Hong-Yang, Wu, Han-Liang, Lin   +6 more
openaire   +2 more sources

RNA interference as a gene knockdown technique

The International Journal of Biochemistry & Cell Biology, 2010
Not many scientific breakthroughs bring significant advances simultaneously in both basic research and translational applications like the discovery of RNA interference. Along with the elucidation of the RNA interference pathway and the discovery of its participation in crucial biological events, a branch of science has grown to utilize the RNA ...
openaire   +2 more sources

Techniques for the Isolation and Use of Conditionally Expressed Antisense RNA to Achieve Essential Gene Knockdowns in Staphylococcus aureus

2008
This chapter provides methods and insights into the use of antisense RNA as a molecular genetic tool. Posttranscriptional inhibition of specific gene expression can be achieved by antisense RNA fragments under control of a conditional promoter. Effective titration of gene expression can cause an apparent null mutation or can be modulated to levels of ...
Allyn, Forsyth, Liangsu, Wang
openaire   +2 more sources