Results 11 to 20 of about 6,611,862 (305)

Evolution by gene loss [PDF]

Nature Reviews Genetics, 2023
The recent increase in genomic data is revealing an unexpected perspective of gene loss as a pervasive source of genetic variation that can cause adaptive phenotypic diversity. This novel perspective of gene loss is raising new fundamental questions: How
Albalat Rodríguez, Ricard, Cañestro García, Cristian   +1 more
core   +4 more sources

Gone with the Species: From Gene Loss to Gene Extinction

Frontiers in Bioscience-Scholar
Background: Vertebrae protein-coding genes exhibit remarkable diversity and are organized into many gene families. These gene families have emerged through various gene duplication events, the most prominent being the two rounds of ...
Ammad Aslam Khan, Anees Fatima
doaj   +3 more sources

Gene Loss DB: a curated database for gene loss in mammals-the cetacean collection. [PDF]

Database (Oxford)
Abstract Molecular databases are essential resources for both experimental and computational biologists. The rapid increase in high-quality genome assemblies has led to a surge in publications describing secondary gene loss events associated with lineage-specific adaptations across diverse vertebrate groups.
Themudo GE, Ruivo R, Valente R, Artilheiro N, Oliveira D, Amorim I, Pinto B, Castro LFC, Fernandes S, Lopes-Marques M.   +9 more
europepmc   +4 more sources

Gene loss during a transition to multicellularity. [PDF]

Sci Rep, 2023
Abstract Multicellular evolution is a major transition associated with momentous diversification of multiple lineages and increased developmental complexity. The volvocine algae comprise a valuable system for the study of this transition, as they span from unicellular to undifferentiated and differentiated multicellular morphologies ...
Jiménez-Marín B, Rakijas JB, Tyagi A, Pandey A, Hanschen ER, Anderson J, Heffel MG, Platt TG, Olson BJSC.   +8 more
europepmc   +5 more sources

The loss of taste genes in cetaceans [PDF]

BMC Evolutionary Biology, 2014
Five basic taste modalities, sour, sweet, bitter, salt and umami, can be distinguished by humans and are fundamental for physical and ecological adaptations in mammals. Molecular genetic studies of the receptor genes for these tastes have been conducted in terrestrial mammals; however, little is known about the evolution and adaptation of these genes ...
Zhu, Kangli, Xu, Shixia, Sun, Di, Ren, Wenhua, Zhou, Kaiya, Yang, Guang, Zhou, Xuming   +6 more
openaire   +4 more sources

Gene Loss and Evolution of the Plastome [PDF]

Genes, 2019
Abstract Chloroplasts are unique organelles within the plant cells and are responsible for sustaining life forms on the earth due to their ability to conduct photosynthesis. Multiple functional genes within the chloroplast are responsible for a variety of metabolic processes that occur in the chloroplast.
Tapan Kumar Mohanta, Awdhesh Kumar Mishra, Adil Khan, Abeer Hashem, Elsayed Fathi Abd_Allah, Ahmed Al-Harrasi   +5 more
openaire   +4 more sources

Extensive loss of Wnt genes in Tardigrada [PDF]

BMC Ecology and Evolution, 2021
AbstractBackgroundWnt genes code for ligands that activate signaling pathways during development in Metazoa. Through the canonical Wnt (cWnt) signaling pathway, these genes regulate important processes in bilaterian development, such as establishing the anteroposterior axis and posterior growth. In Arthropoda, Wnt ligands also regulate segment polarity,
Chavarria, Raul A., Game, Mandy, Arbelaez, Briana, Ramnarine, Chloe, Snow, Zachary K., Smith, Frank W.   +5 more
openaire   +4 more sources

Gene therapy for hearing loss [PDF]

Human Molecular Genetics, 2019
Abstract Sensorineural hearing loss (SNHL) is the most common sensory disorder. Its underlying etiologies include a broad spectrum of genetic and environmental factors that can lead to hearing loss that is congenital or late onset, stable or progressive, drug related, noise induced, age related, traumatic or post-infectious. Habilitation
Ryotaro Omichi, Seiji B Shibata, Cynthia C Morton, Richard J H Smith   +3 more
openaire   +2 more sources

Phylogenetic reconstruction with gene rearrangements and gene losses [PDF]

2010 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), 2010
Reconstructing phylogenies from gene-order data has become very attractive in the research of evolution these years. So far, most methods can only treat genomes with equal gene contents with each gene appearing exactly once in each genome. In this paper, we propose a new distance measurement for genomes with inversions and insertions/deletions that ...
Yiwei Zhang, Fei Hu, Jijun Tang
openaire   +1 more source

Gene Loss and Movement in the Maize Genome [PDF]

Genome Research, 2004
Maize (Zea mays L. ssp. mays), one of the most important agricultural crops in the world, originated by hybridization of two closely related progenitors. To investigate the fate of its genes after tetraploidization, we analyzed the sequence of five duplicated regions from different chromosomal locations.
Lai J., Ma J., Swigonová Z., Ramakrishna W., Linton E., Llaca V., Tanyolac B., Park Y.-J., Jeong O.-Y., Bennetzen J.L., Messing J.   +10 more
openaire   +3 more sources